China Precision Medicine Pathologist & Lab Leader

BioSpace; Shanghai (VA); Vor Ort; USD 180.000 - 260.000; Vollzeit

Benefits dieser Stelle

Health insurance

Zusammenfassung

AbbVie in the China Precision Medicine division seeks a Pathologist/Pathology Lab Leader to provide expertise in human disease pathology and to lead tissue-based assay development across therapeutic areas. You will oversee pathology lab setup, project management, data analysis and interpretation of testing results.

The role emphasizes leadership of pathology teams, development of biomarker assays, validation of diagnostics, and collaboration with project teams and CROs to advance CDx strategies

Qualifikationen

• Experienced pathologist (MD) or PhD with relevant post-doctoral academic, clinical and/or industry pathology experience -required
• Board certification in pathology (anatomic, clinical, combined, with or without additional specialization) – preferred
• Proven track record with pathology lab/team/project leadership and pathology assay development/validation

Aufgaben

• Lead China pathology lab/project development teams or sub-teams. Coordinate with appropriate team members to advance projects efficiently. Focus of the position will be to provide pathology support needed for spatial biology and single cell genomics.
• Contribute to or Lead the design and interpretation of tissue-based studies investigating aspects such as target biology, drug MOA, target pathway activation, pharmacodynamic effects, biomarker prevalence, or drug distribution.
• Contribute To The Design, Validation And Deployment Of Pathology Assays, Including The Determination Of Assay Parameters Such As Specificity And Sensitivity. Design, Implement And Oversee Pathology-based Biomarker And Diagnostic Testing, Including Data Analysis
• Develop, validate and implement scoring paradigms for tissue-based assays
• Direct the development, outsourcing and validation of clinically applicable tissue-based assays. Assist in the development of assay protocols as needed.
• Provide Pathology Input To Project Teams And Ensure Access To State-of-the-art Tissue-based Techniques And Samples For Target Pathway Evaluation In Human Disease
• Implement technologies and/or methodologies via a combination of in-house efforts and the use of CROs or other external expertise using techniques such as in situ hybridization, immunohistochemistry (including multiplexed), spatial biology image analysis, etc.
• Evaluate the scientific basis and clinical applicability of the proposed assays, their validation status and any related technical issues.
• Assume responsibility for the assessment and scoring of specimens and the preparation of reports summarizing the data, analysis and interpretation of findings.
• Write the relevant pathology-based biomarker and diagnostics testing sections in drug development and registration documents such as clinical study protocols, clinical study reports, investigator brochures, and regulatory submission packages (INDs, NDA’s, BLA's).
• Collaborate with project teams from concept to reagent generation to quantitation and approval plan for CDx as needed.
• Participate in the evaluation of external licensing or collaborative opportunities (including CDx collaborations) and oversee internal components of shared programs.

Jobbeschreibung

AbbVie in the China Precision Medicine division seeks a Pathologist/Pathology Lab Leader to provide expertise in human disease pathology and to lead tissue-based assay development across therapeutic areas. You will oversee pathology lab setup, project management, data analysis and interpretation of testing results.

The role emphasizes leadership of pathology teams, development of biomarker assays, validation of diagnostics, and collaboration with project teams and CROs to advance CDx strategies