Biophysics Scientist: ML-Enhanced Drug Discovery

Amgen; Thousand Oaks (CA); On-site; USD 120,000 - 180,000; Full time

Job summary

Amgen is seeking a Biophysics Scientist in Thousand Oaks to join a team focused on discovering innovative biologics. You will perform high-throughput SPR-based binding characterization and study cross-species selectivity to support our drug discovery pipeline, while producing rigorous data and communicating results clearly.

The role emphasizes collaboration with computational sciences to apply ML/AI methods and interface with multiple scientific teams, contributing to a scientifically rigorous,

Qualifications

• PhD, PharmD, MD or equivalent with required experience.
• Experience with binding analysis using Surface Plasmon Resonance (SPR).
• Excellent written and oral communication skills.
• Ability to collaborate across functions and teams.

Responsibilities

• Perform high-throughput binding affinity characterization using SPR.
• Determine cross-species selectivity and investigate mechanism of action in binding interactions.
• Generate and analyze scientific data; communicate results clearly, both orally and in writing.
• Collaborate with scientists across functions and interface with Computational Sciences Group.
• Contribute to development of ML/AI models to improve molecular attributes.

Skills

SPR binding

Data analysis

Communication

Team collaboration

ML/AI modeling

Education

PhD

PharmD

MD

Master's + 3 yrs

Bachelor's + 5 yrs

Tools

Bravo automation

Hamilton liquid handler

Job description

Amgen is seeking a Biophysics Scientist in Thousand Oaks to join a team focused on discovering innovative biologics. You will perform high-throughput SPR-based binding characterization and study cross-species selectivity to support our drug discovery pipeline, while producing rigorous data and communicating results clearly.

The role emphasizes collaboration with computational sciences to apply ML/AI methods and interface with multiple scientific teams, contributing to a scientifically rigorous,