Senior Scientist - Translational Oncology & Biomarkers

Genentech; South San Francisco (CA); On-site; USD 121,000 - 224,000; Full time

Benefits offered by this job

Discretionary annual bonus

Benefits package

Job summary

Genentech is seeking a Scientist 3 in Translational Medicine (Oncology) based in California. You will design and execute experiments to validate hypotheses from non-clinical to real-world data and lead biomarker-driven strategies to accelerate clinical development.

You will collaborate across teams to elucidate mechanisms of action, develop fit-for-purpose assays, and apply multi-omic approaches to address biomarker questions. A Ph.D. and strong communication skills are required.

Qualifications

• Ph.D. in Cancer Biology, Cell Biology, Immunology or related disciplines; BA/BS/MS with related experience considered.
• Deep understanding of cancer biology, cancer immunology and immunotherapy mechanisms.
• Proven ability to lead hands-on lab-based research and to develop relevant assays.

Responsibilities

• Design and execute experiments to validate biological and therapeutic hypotheses derived from non-clinical, clinical, and real-world data.
• Synthesize, analyze, and interpret experimental and computational data in collaboration with other functions.
• Elucidate mechanisms of action and resistance to guide patient selection and biomarker assessment.
• Identify and validate cell-based, biochemical, and multi-omic assays for scalable testing.
• Establish collaborations to access emerging technologies and datasets for translational innovation.

Skills

Cancer biology

Immunology

Immunotherapies / targeted therapies

Single-cell & multi-omics profiling

Lab-based research leadership

Education

Ph.D. in Cancer Biology, Cell Biology, Immunology

BA/BS or MS with 6+ years related experience

Tools

Flow cytometry

Preclinical models

Spatial transcriptomics

Single-cell & multi-omics platforms

Job description

Genentech is seeking a Scientist 3 in Translational Medicine (Oncology) based in California. You will design and execute experiments to validate hypotheses from non-clinical to real-world data and lead biomarker-driven strategies to accelerate clinical development.

You will collaborate across teams to elucidate mechanisms of action, develop fit-for-purpose assays, and apply multi-omic approaches to address biomarker questions. A Ph.D. and strong communication skills are required.