Biology Associate Director — Preclinical Oncology Leader

Ratio Therapeutics; Boston (MA); On-site; USD 175,000 - 200,000; Full time

Job summary

Ratio Therapeutics in Boston, MA is seeking an Associate Director in Biology to lead preclinical biology and pharmacology initiatives. The role involves directing in vivo and in vitro studies, coordinating cross-functional teams, and advancing radioligand therapy programs toward IND submissions.

The ideal candidate will have a Ph.D. with 10+ years (or M.S. with 15+ years), strong leadership, hands-on lab experience, and a track record of scientific excellence.

Qualifications

• Ph.D. in cancer biology or related field with 10+ years, or Master’s with 15+ years of industry experience.
• Deep subject matter expertise in tumor biology surrounding current and new targets.
• Proven ability and willingness to engage in hands-on laboratory work to advance research objectives.
• Familiarity with or use of radioactivity or radioactive assays preferred.
• Experience managing scientific teams in a biotech or pharmaceutical setting.
• Excellent problem-solving skills, attention to detail, and ability to work independently with minimal supervision.
• Demonstrated pursuit of quality and excellence in innovation and execution.
• Integrity, respect, and compassion for colleagues, collaborators, and the patients we serve.

Responsibilities

• Lead and execute in vivo pharmacology studies (biodistribution, pharmacokinetics) in cell line and patient-derived xenografts for compound evaluation.
• Manage multiple projects involving internal stakeholders, external collaborators and CROs in a fast-paced collaborative environment.
• Manage and oversee the day-to-day activities of a talented group of in vivo scientists.
• Partner with cross-functional teams, including chemistry, radiochemistry, clinical, and regulatory, to ensure successful project progression.
• Contribute to the preparation of regulatory submissions, including Investigational New Drug (IND) applications.
• Ensure all biological research complies with applicable regulatory standards and guidelines.
• Communicate results effectively with internal stakeholders and align on future directions.
• Demonstrate experience working collaboratively within and across teams in a complex, matrix environment.
• Demonstrate strong interpersonal, organizational skills and leverage team work to create innovative solutions and achieve common goals.

Skills

Team leadership

Independent research

Strong communication

Problem solving

Education

Ph.D. in cancer biology

M.S. in related field

Tools

Radioactivity assays

Job description

Ratio Therapeutics in Boston, MA is seeking an Associate Director in Biology to lead preclinical biology and pharmacology initiatives. The role involves directing in vivo and in vitro studies, coordinating cross-functional teams, and advancing radioligand therapy programs toward IND submissions.

The ideal candidate will have a Ph.D. with 10+ years (or M.S. with 15+ years), strong leadership, hands-on lab experience, and a track record of scientific excellence.