Executive Director / VP, Clinical Pharmacology D300-1065

GRN Boston North; United States; Remote; USD 290,000 - 330,000; Full time

Job summary

GRN Boston North is seeking an Executive Director / VP, Clinical Pharmacology to lead the clinical pharmacology strategy across oncology programs in a remote US setting. This senior role requires 10–15+ years in oncology clinical pharmacology, a PhD or PharmD, and a track record in regulatory submissions and cross-functional leadership.

Compensation includes a base salary of $290,000–$330,000 plus bonus, equity, and full benefits.

Qualifications

• PhD or PharmD required; oncology experience preferred.
• 10–15+ years in oncology clinical pharmacology.
• Experience with regulatory submissions and IND/CTA/NDA processes.

Responsibilities

• Lead the clinical pharmacology strategy across multiple oncology programs, ensuring scientific rigor and regulatory alignment.
• Oversee the design and execution of clinical pharmacology studies, including first-in-human and proof-of-concept trials.
• Apply model-informed drug development (MIDD) approaches, including PBPK, PK/PD, population PK, and exposure-response analyses.
• Serve as regulatory lead for clinical pharmacology, authoring IND, CTA, NDA modules and engaging with FDA/global health authorities.
• Collaborate with cross-functional leaders in clinical operations, regulatory, biostatistics, and translational medicine to advance pipeline assets.
• Stay on the forefront of innovation in clinical pharmacology and oncology, contributing thought leadership to the field.

Skills

Clinical pharmacology

Regulatory submissions

Cross-functional leadership

PBPK modeling

PK/PD analyses

Education

PhD or PharmD

Job description

Executive Director / VP, Clinical Pharmacology
US, Remote

Required Experience:

Clinical Pharmacology, 10+ years

Required Experience:

Clinical Pharmacology, 10+ years

• Team managment, +5 years
• Pharma Bio industry, 15+ years

Required Education:

PhD or Pharm D, preferred

Required Education:

PhD or Pharm D, preferred

Job Description

Executive Director / Vice President – Clinical Pharmacology

Confidential Clinical-Stage Biopharma (Oncology Focus)

Company Overview

• Therapeutic Area: Oncology, with emphasis on RAS- and Kinase-driven malignancies
• Stage: Clinical-stage, expanding rapidly across research, clinical, and translational functions
• Culture: Agile, science-driven, collaborative, with a mission-oriented focus on improving patient outcomes

Position Highlights

Title: Executive Director / Vice President, Clinical Pharmacology, Remote US

Location: Remote (U.S. based, with strong preference for major biotech hubs)

Compensation: $290,000 - $330,000 base + bonus, equity, and full benefits

Key Responsibilities

• Lead the clinical pharmacology strategy across multiple oncology programs, ensuring scientific rigor and regulatory alignment.
• Oversee the design and execution of clinical pharmacology studies, including first-in-human and proof-of-concept trials.
• Apply model-informed drug development (MIDD) approaches, including PBPK, PK/PD, population PK, and exposure-response analyses.
• Serve as regulatory lead for clinical pharmacology, authoring IND, CTA, NDA modules and engaging with FDA/global health authorities.
• Collaborate with cross-functional leaders in clinical operations, regulatory, biostatistics, and translational medicine to advance pipeline assets.
• Stay on the forefront of innovation in clinical pharmacology and oncology, contributing thought leadership to the field.

Ideal Candidate Profile

• Ph.D. or equivalent in Clinical Pharmacology, Pharmacokinetics/Pharmacodynamics, or related field
• 10-15+ years of experience in oncology clinical pharmacology, ideally with small molecules in solid tumors
• Strong track record of regulatory submissions and successful advancement of oncology programs into late-stage development
• Expertise in quantitative pharmacology (PBPK, exposure-response, population PK/PD)
• Excellent cross-functional leadership skills and ability to operate in a fast-paced biotech environment

Why This Role is Attractive

• Impact: Lead clinical pharmacology strategy in a company poised to change treatment paradigms in oncology
• Visibility: Direct interaction with executive leadership and global regulators
• Growth: Opportunity to shape multiple oncology programs and influence portfolio strategy
• Rewards: Competitive total compensation with equity participation in a high-growth biopharma

GRN Boston North

633 Waverly Road

Suite 100

North Andover, MA 01845 USA