Analytical Development Scientist: Cell Lines & Bioassays

Vertex Pharmaceuticals Incorporated

Boston (MA)

On-site

USD 103,000 - 154,000

Full time

6 days ago

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Benefits offered by this job

Annual bonus

Equity awards

Paid time off

Commuting subsidy

Educational assistance

Job summary

Vertex is seeking a highly motivated Scientist to join the Analytical Development team in Boston, MA. This role leads development of analytical cell lines as reagents for potency assay development and validation of bioassays for biologics.

Collaborate across Research and Analytical Development to translate mechanism of action into cell line and assay strategies. The candidate will design and optimize cell-based assays, transfer knowledge to internal/external partners, and mentor junior staff

Qualifications

PhD in Cell Biology, Molecular Biology, Biochemistry, Immunology, or related field with 0–3 years industry experience in biologics analytical development.
Master’s in biology with 3 years of work experience in biopharma industry or
Bachelor’s in biology with 6 years of work experience in biopharma industry.
Experience developing analytical cell lines and cell-based potency or functional assays.

Responsibilities

Lead the design, characterization and lifecycle management of stable mammalian analytical cell lines expressing targets of interest, receptor systems, or reporter constructs to support potency and functional bioassays.
Manage CROs for the development of cell lines for use in bioassays. Act as the primary point of contact to provide technical guidance and ensure alignment with project goals and timelines.
Translate product mechanism of action into cell line designs and cell-based assay concepts aligned with potency and analytical control strategy.