Analytical Development Scientist, Bioassays & Cell Lines

Vertex Pharmaceuticals LLC

Boston (MA)

On-site

USD 103,000 - 154,000

Full time

6 days ago
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Benefits offered by this job

Annual bonus
Equity awards
Medical, dental, vision coverage
Paid time off
Educational assistance
Commuting subsidy

Job summary

Vertex Pharmaceuticals LLC in Boston, MA, seeks an Analytical Development Scientist to lead development of analytical cell lines for potency assays and for characterization of biologics. You will translate mechanism of action into cell line and assay strategies, work across Research and Analytical Development, and manage CROs to meet project timelines.

The role requires a strong background in bioassay development, cell line engineering, and experience with ELISA, reporter assays, and

Qualifications

  • Ph.D. in Cell Biology or related field with industry experience in biologics analytical development or bioassay design.
  • Master’s in biology with relevant experience in biopharmaceutical analytics.
  • Bachelor’s in biology with significant industry experience in biopharmaceutical analytics.

Responsibilities

  • Lead development of analytical cell lines for potency and functional bioassays.
  • Develop, validate and transfer cell-based bioassays (e.g., reporter gene, signaling, cytotoxicity).
  • Collaborate across Research and Analytical Development and manage CROs as needed.
  • Ensure data integrity and regulatory readiness of documentation.

Skills

Bioassay development
Plate-based assays
ELISA
Reporter gene assays
Cytotoxicity assays
Flow cytometry
qPCR/ddPCR
Data analysis

Education

PhD in Cell Biology
Master's in Biology
Bachelor's in Biology

Tools

JMP
GraphPad Prism
SoftMax Pro

Job description

Vertex Pharmaceuticals LLC in Boston, MA, seeks an Analytical Development Scientist to lead development of analytical cell lines for potency assays and for characterization of biologics. You will translate mechanism of action into cell line and assay strategies, work across Research and Analytical Development, and manage CROs to meet project timelines.

The role requires a strong background in bioassay development, cell line engineering, and experience with ELISA, reporter assays, and

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