ADME Project Lead - Genetic Medicines

BioSpace; Boston (MA); On-site; USD 194,000 - 339,000; Full time

Job summary

Lilly in Boston seeks an ADME/DMPK scientist to lead ADME studies and support preclinical and clinical development of gene therapies. The role emphasizes integrating ADME/PK/PD with discovery data, designing hypothesis-driven studies, and collaborating with biology and chemistry teams to guide drug design and delivery.

Strong written and verbal communication is essential, with experience preparing regulatory documents and mentoring colleagues across levels.

Qualifications

• Ph.D. in Biochemistry/Biology/Pharmacokinetics/Bioengineering/Pharmacology or related field.
• Greater than five years of experience in a pharmaceutical/biotech company in an ADME or PK/PD role.

Responsibilities

• Lead and innovate in ADME studies to support preclinical and clinical development of Lilly genetic medicines.
• Integrate ADME/PK/PD data with discovery chemistry and biology to guide design and delivery.
• Design, implement, and interpret mechanistic ADME, PK/PD, and TK studies.
• Collaborate with cross-functional colleagues across discovery and development.
• Lead ADME portions of regulatory communications to support clinical programs and NDA filings.

Skills

ADME knowledge

PK/PD knowledge

Regulatory knowledge

Data interpretation

Education

PhD in Biochemistry/Biology/Pharmacokinetics/Bioengineering/Pharmacology

Tools

LC/MS

PCR

Immunoassay

Job description

Lilly in Boston seeks an ADME/DMPK scientist to lead ADME studies and support preclinical and clinical development of gene therapies. The role emphasizes integrating ADME/PK/PD with discovery data, designing hypothesis-driven studies, and collaborating with biology and chemistry teams to guide drug design and delivery.

Strong written and verbal communication is essential, with experience preparing regulatory documents and mentoring colleagues across levels.