Remote Senior Scientist: Structure-Based Modeling & MD/FEP

Deep Origin; Portugal; Remote; EUR 50,000 - 75,000; Full time

Benefits offered by this job

Competitive salary and equity packages

Flexible working hours

Mission-driven culture

Job summary

A leading biotech company in Portugal is looking for a Scientist or Senior Scientist with expertise in structure-based drug design. The role involves designing simulations, analyzing protein-ligand structures, and collaborating with various teams. Candidates must have a Ph.D. and relevant experience in molecular dynamics and docking. This position offers competitive salary and a flexible, remote-first work environment.

Qualifications

• 2+ years of postdoctoral or industry experience in structure-based modeling.
• Hands-on expertise with free energy perturbation (FEP).
• Strong understanding of protein-ligand binding and conformational variability.

Responsibilities

• Analyze protein targets focusing on conformations and binding site flexibility.
• Run and refine docking and molecular dynamics simulations.
• Collaborate with cheminformatics and experimental teams.

Skills

Expertise in structure-based drug design

Molecular dynamics simulation

Docking

Programming in Python

Fluency in English

Education

Ph.D. in computational chemistry or related field

Tools

GROMACS

OpenMM

Schrödinger FEP+

Job description

A leading biotech company in Portugal is looking for a Scientist or Senior Scientist with expertise in structure-based drug design. The role involves designing simulations, analyzing protein-ligand structures, and collaborating with various teams. Candidates must have a Ph.D. and relevant experience in molecular dynamics and docking. This position offers competitive salary and a flexible, remote-first work environment.