Technical Operator (GMP) – Automated Manufacturing

SIRE LIFE SCIENCES; Breda; On-site; EUR 42,000 - 54,000; Full time

Job summary

SIRE LIFE SCIENCES in Breda is seeking a Technical Operator (GMP) – Automated Manufacturing to help run a highly automated GMP-regulated production environment. You will operate equipment, perform routine checks, record data, and support improvements to keep lines running safely and efficiently.

You'll work with Production, Engineering, Maintenance and Quality teams, handle setup and changeovers, review data in SAP/MES, investigate deviations, and contribute to Lean and continuous improvement

Qualifications

• MBO-level technical qualification or equivalent experience.
• Experience working within manufacturing, production, processing, or other industrial operations.
• Experience operating or supporting automated machinery or technology-driven production environments.
• Knowledge of GMP requirements and quality-focused ways of working.
• Experience with production software or digital manufacturing systems such as SAP, MES, or similar platforms.

Responsibilities

• Ensure production activities are completed according to GMP, quality, and safety standards.
• Operate automated equipment used for manufacturing, assembly, labeling, and packaging activities.
• Prepare production lines for new batches, including equipment set-up, changeovers, cleaning, and line clearance activities.
• Review and record manufacturing data using SAP and MES.
• Investigate process deviations and support Root Cause Analysis (RCA / 5 Why).
• Identify opportunities to improve workflows, equipment performance, and operational efficiency through Lean Manufacturing and Continuous Improvement initiatives.
• Work closely with Production, Engineering, Maintenance, and Quality teams to solve day-to-day operational challenges.
• Perform routine inspections, equipment adjustments, and basic first-line maintenance tasks.
• Monitor production performance and take appropriate action when abnormalities occur.
• Support a culture of teamwork, innovation, operational excellence, and continuous improvement.

Skills

GMP

Problem solving

English

Ownership

Lean Manufacturing

Education

MBO-level technical qualification

Tools

SAP

MES

Job description

Company:

A global biotechnology company dedicated to improving patients' lives through innovative medicines. The Breda manufacturing site is a highly automated, GMP-regulated facility responsible for the production, labeling, assembly, and distribution of medicines to more than 75 countries worldwide. The company values innovation, operational excellence, continuous improvement, and collaboration while providing employees with excellent career development opportunities.

Job Description:

As a Technical Operator (GMP) – Automated Manufacturing, you'll play an important role in the day-to-day running of our manufacturing operation. Working within a GMP-regulated environment, you'll help ensure products are produced safely, efficiently, and to the highest quality standards. You'll work with advanced production equipment, support troubleshooting activities when issues arise, and help keep manufacturing processes running smoothly. Whether it's operating equipment, carrying out routine checks, recording production data, or identifying improvements, you'll be a key part of a team focused on delivering reliable results. This position is ideal for someone who enjoys a hands-on technical role, likes solving problems, and wants to contribute to a modern manufacturing environment where quality, safety, and continuous improvement are at the heart of everything we do.

Responsibilities:

• Ensure production activities are completed according to GMP, quality, and safety standards.
• Operate automated equipment used for manufacturing, assembly, labeling, and packaging activities.
• Prepare production lines for new batches, including equipment set-up, changeovers, cleaning, and line clearance activities.
• Review and record manufacturing data using digital systems such as SAP and Manufacturing Execution Systems (MES).
• Investigate process deviations and support Root Cause Analysis (RCA / 5 Why) to prevent recurring issues.
• Identify opportunities to improve workflows, equipment performance, and operational efficiency through Lean Manufacturing and Continuous Improvement initiatives.
• Work closely with colleagues from Production, Engineering, Maintenance, and Quality teams to solve day-to-day operational challenges.
• Perform routine inspections, equipment adjustments, and basic first-line maintenance tasks.
• Monitor production performance and take appropriate action when abnormalities occur.
• Support a culture of teamwork, innovation, operational excellence, and continuous improvement.

Requirements:

This opportunity is ideal for someone who enjoys working in a technical environment, likes finding practical solutions, and takes pride in maintaining high standards of quality and compliance. We'd love to hear from you if you have:

• MBO-level technical qualification or equivalent experience.
• Experience working within manufacturing, production, processing, or other industrial operations.
• Experience operating or supporting automated machinery or technology-driven production environments.
• Strong problem-solving skills with a structured approach to troubleshooting.
• Previous experience within a GMP-regulated or other quality-controlled industry, such as pharmaceuticals, biotechnology, medical devices, food production, or chemicals.
• Knowledge of GMP requirements and quality-focused ways of working.
• Experience with production software or digital manufacturing systems such as SAP, MES, or similar platforms.
• A proactive attitude with a high level of ownership, accountability, and attention to detail.
• Good communication skills in English.
• Willingness to work a rotating 3-shift or 5-shift schedule.

Other Information:

This is an excellent opportunity to join a global biotechnology leader and work in a highly automated, GMP-regulated manufacturing environment. You'll benefit from competitive compensation, career development opportunities, and a collaborative, innovative workplace while contributing to the production of life-changing medicines for patients worldwide.