Chemical Process Engineer

Walter Bushnell; Kolkata District; On-site; INR 1,000,000 - 1,400,000; Full time

Job summary

Walter Bushnell Research & Development Center Pvt. Ltd. in Kolkata seeks a Chemical Process Engineer for API R&D to develop and optimize scalable API synthesis, ensure safety and regulatory readiness, and support tech transfer to manufacturing.

You will work with cross‑functional teams, apply DoE, perform PFDs/PDIs, and contribute to DMFs and QbD filings, leveraging flow chemistry and continuous processing where applicable.

Qualifications

• Bachelor's or Master's degree in Chemical Engineering.
• 58 years of API process development/R&D experience.
• Strong knowledge of reaction engineering, kinetics, and unit operations.
• Familiarity with cGMP, ICH guidelines, QbD for APIs.
• Hands-on experience with lab-scale and kilo-lab equipment.
• Experience with process simulation tools such as Aspen Plus, ChemCAD, or equivalent is preferred.

Responsibilities

• Develop and optimize synthetic processes for APIs at lab and kilo scale.
• Design and execute DoE experiments and reaction engineering studies for unit operations.
• Assess scalability, safety, and technology transfer to manufacturing plants.
• Perform material and energy balances, process simulations, and equipment sizing.
• Prepare and maintain process documentation (PFDs, P&IDs, risk assessments, transfer dossiers).
• Conduct and participate in process hazard analyses (PHA), HAZOP studies, and safety evaluations.
• Troubleshoot scale-up and manufacturing issues with production teams.
• Support regulatory documentation including DMFs and QbD filings.
• Collaborate with Analytical R&D, QA, and EHS.
• Stay updated with modern API manufacturing technologies like flow chemistry and continuous processing.

Skills

Reaction engineering

Kinetics

Unit operations

Education

Bachelor's/Master's in Chemical Engineering

Tools

Aspen Plus

ChemCAD

Job description

Company: Walter Bushnell Research & Development Center Pvt. Ltd.

Job Title: Chemical Process Engineer -API R&D

Location: Kolkata

Department: Research & Development (API)

Reporting To: R&D Manager / Head Process Development

Employment Type: Full-Time

Role Overview

We are seeking a skilled and motivated Chemical Engineer to join our API R&D team. The role involves developing and optimizing chemical processes, ensuring scalability, safety, and efficiency, and supporting seamless technology transfer to manufacturing.

Key Responsibilities

• Develop and optimize synthetic processes for Active Pharmaceutical Ingredients (APIs) at lab and kilo scale in collaboration with chemists and process scientists.
• Design and execute experiments using Design of Experiments (DoE) and conduct reaction engineering studies for critical unit operations.
• Assess process scalability, safety, and sustainability to enable efficient technology transfer to manufacturing plants.
• Perform material and energy balances, process simulations, and equipment sizing.
• Prepare and maintain comprehensive process documentation, including PFDs, P&IDs, risk assessments, scale-up reports, and technology transfer dossiers.
• Conduct and participate in process hazard analysis (PHA), HAZOP studies, and safety evaluations.
• Troubleshoot issues related to scale-up and manufacturing in coordination with production teams.
• Support preparation of regulatory documentation, including DMFs and QbD filings.
• Collaborate with cross-functional teams such as Analytical R&D, Quality Assurance, and EHS.
• Stay updated with and apply modern API manufacturing technologies such as flow chemistry, continuous processing, and photochemistry.

Qualifications & Experience

• Bachelors or Masters degree in Chemical Engineering (B.E./B.Tech or M.E./M.Tech).
• 58 years of experience in API process development or pharmaceutical R&D.
• Strong knowledge of chemical reaction engineering, kinetics, and unit operations.
• Familiarity with cGMP, ICH guidelines, QbD principles, and regulatory requirements for APIs.
• Hands-on experience with lab-scale and kilo-lab equipment (reactors, filtration, drying systems).
• Experience with process simulation tools such as Aspen Plus, ChemCAD, or equivalent is preferred.