Senior Scientist, Biologics Downstream Process Development

Bristol-Myers Squibb Co; Cruiserath; On-site; EUR 90,000 - 120,000; Full time

Benefits offered by this job

Annual bonus

Pension contribution

Family health insurance

27 days annual leave

Access to BMS Cruiserath on-site gym

Life assurance

Job summary

Bristol Myers Squibb is seeking a Senior Scientist in Manufacturing - Process Development at the Cruiserath site in Ireland. You will lead downstream unit operations for commercial biologics, drive tech transfer, and support investigations and regulatory responses.

The role requires strong GMP knowledge, scientific writing and cross-functional collaboration to ensure robust, compliant processes and continuous improvement across the network.

Qualifications

• Degree in chemical or biochemical engineering, biochemistry, biotechnology or related scientific discipline.
• Relevant biopharmaceutical industry experience commensurate with Senior Scientist level (7+ yrs for bachelor; 5+ for master; 2–4 yrs for PhD).
• Strong understanding of protein purification, stability and downstream performance.
• Experience with downstream processing operations and equipment (chromatography, ultrafiltration).
• Experience supporting commercial manufacturing, technology transfer, validation or investigations in a regulated environment.
• Ability to analyse complex technical issues and provide evidence-based recommendations.
• Strong writing, presentation and stakeholder communication skills.
• Working knowledge of GMP expectations and regulatory impact of decisions.

Responsibilities

• Provide technical leadership for downstream unit operations in commercial biologics manufacturing.
• Lead tech transfer of assets to Cruiserath and wider network with oversight and recommendations.
• Lead or support process troubleshooting, investigations and CAPA.
• Design and interpret lab or scale-down studies for investigations, understanding and transfer.
• Author and review protocols, technical reports, regulatory content and responses.
• Drive continuous improvement to robustness, efficiency, and knowledge management.
• Collaborate across MS&T, Manufacturing, Quality, Process Development and external partners.

Skills

Downstream processing

Tech transfer

Process development

GMP knowledge

Scientific writing

Stakeholder communication

Education

Chemical/biochemical engineering or related

Biochemistry/biotechnology degree

Tools

Chromatography systems

Ultrafiltration/diafiltration

Process-scale equipment

Job description

Bristol Myers Squibb is seeking a Senior Scientist in Manufacturing - Process Development at the Cruiserath site in Ireland. You will lead downstream unit operations for commercial biologics, drive tech transfer, and support investigations and regulatory responses.

The role requires strong GMP knowledge, scientific writing and cross-functional collaboration to ensure robust, compliant processes and continuous improvement across the network.