Senior Scientist, Manufacturing - Process Development Cruiserath - IE R1607862 Posted 20 hours ago

Bms; Cruiserath; Remote; EUR 95,000 - 130,000; Full time

Benefits offered by this job

Annual bonus

Pension contribution

Family health insurance

27 days annual leave

On-site gym at Cruiserath

Life assurance

Job summary

Bristol Myers Squibb in Cruiserath, Ireland, is seeking a Senior Scientist, Manufacturing - Process Development, to lead downstream unit operations and support tech transfer for commercial biologics. You will collaborate across MS&T, Manufacturing and Quality to ensure robust, compliant processes.

The role emphasizes project leadership, complex data analysis, and effective scientific communication in a regulated environment. Strong emphasis on GMP and continuous improvement.

Qualifications

• Degree in chemical or biochemical engineering, biochemistry, biotechnology or related.
• Bachelor’s 7+ years, Master’s 5+ years, or PhD 2–4 years of relevant experience.
• Strong understanding of protein purification, protein stability and downstream performance.
• Experience with downstream processing equipment incl chromatography and ultrafiltration/diafiltration.
• Experience in regulated manufacturing, tech transfer, validation or investigations.
• Ability to analyze complex technical issues and write clear, evidence-based recommendations.
• GMP knowledge and data integrity are important.

Responsibilities

• Provide technical leadership for downstream unit operations supporting commercial biologics manufacturing.
• Lead tech transfer of assets to Cruiserath and broader network with oversight.
• Lead or support troubleshooting, investigations, and CAPA development.
• Design, execute, and interpret lab or scale-down studies for investigations and tech transfer.
• Author and review study protocols, technical reports, and regulatory content.
• Drive continuous improvement for robustness, efficiency, and knowledge management.
• Collaborate across MS&T, Manufacturing, Quality, Process Development and Regulatory teams.

Skills

Protein purification

Protein stability

Downstream processing

Tech transfer

Scientific writing

Data analysis

Education

Bachelor’s degree in chemical/biochemical engineering or related

Master’s degree in chemical/biochemical engineering or related

PhD in related field

Tools

Chromatography systems

Ultrafiltration/ diafiltration

Process-scale equipment

Job description

## Senior Scientist, Manufacturing - Process DevelopmentCruiserath - IEFind out how well you match with this jobAt Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it. # Key Responsibilities· Provide technical leadership and subject matter expertise for downstream unit operations supporting commercial biologics manufacturing.· Led tech transfer of commercial and pipeline assets to the Cruiserath facility and wider network, providing technical oversight and recommendations.· Lead or support process troubleshooting, root cause analysis, investigations and the development of scientifically sound corrective and preventive actions.· Design, execute and interpret laboratory or scale-down studies that support manufacturing investigations, process understanding and technology transfer.· Author and review study protocols, technical reports, scientific assessments, regulatory submission content and responses to technical enquiries.· Drive continuous improvement initiatives that enhance process robustness, efficiency, compliance and knowledge management.· Collaborate across MS&T, Manufacturing, Quality, Process Development, Analytical, Regulatory and external partner organisations to align technical strategy and execution.· Evaluate emerging downstream technologies and recommend fit-for-purpose improvements where these could strengthen manufacturing performance.· Mentor and coach scientists and engineers, supporting effective technical decision-making and the development of downstream capability.# Technical ScopeThe role may support technical studies and manufacturing activities across the following downstream operations:· Protein chromatography· Viral inactivation· Viral filtration· Ultrafiltration and diafiltration· Membrane and depth filtration· Primary recovery and centrifugation· Process-scale and laboratory-scale downstream equipment, including chromatography and filtration systems# Required Qualifications and Experience· Degree in chemical or biochemical engineering, biochemistry, biotechnology or a related scientific discipline.· Relevant biopharmaceutical industry experience commensurate with the Senior Scientist level. As an initial benchmark: bachelor’s degree with at least 7 years, master’s degree with at least 5 years, or PhD with approximately 2 to 4 years of relevant experience.· Strong scientific understanding of protein purification, protein stability and downstream process performance.· Demonstrated experience with downstream processing operations and equipment, including chromatography and ultrafiltration/diafiltration systems.· Experience supporting commercial manufacturing, process development, technology transfer, validation or manufacturing investigations in a regulated environment.· Ability to independently analyse complex technical issues, integrate multiple data sources and develop clear, evidence-based recommendations.· Strong technical writing, presentation and stakeholder communication skills.· Working knowledge of GMP expectations and the potential manufacturing and regulatory impact of technical decisions.# Preferred Qualifications· Experience with process characterisation, scale-down model qualification or continued process verification.· Experience leading technical transfer activity and support commercial manufacture· Experience authoring or contributing to CMC documentation and supporting regulatory inspections or technical responses.· Demonstrated experience mentoring colleagues or providing technical leadership within cross-functional teams.· Experience applying structured problem-solving, statistical analysis or design of experiments to bioprocess challenges.# Core Competencies**Scientific leadership**Applies deep technical knowledge and sound judgement to complex downstream challenges.**Execution**Plans and delivers high-quality technical work with appropriate urgency, rigour and documentation.**Collaboration**Builds productive relationships across functions, sites and external partners.**Communication**Conveys technical data, risk and recommendations clearly to scientific and non-scientific audiences.**Problem-solving**Uses structured, evidence-based approaches to identify root causes and sustainable solutions.**Coaching**Shares knowledge, provides constructive guidance and helps build team capability.**Compliance mindset**Understands GMP impact and maintains high standards of data integrity and documentation.**Continuous improvement**Identifies and implements practical opportunities to improve robustness and efficiency.# Working Environment and Role Expectations· Work is performed through a combination of office and laboratory-based activities, subject to site requirements.· The role requires effective prioritisation across planned studies, manufacturing support and time-sensitive technical issues.· The successful candidate is expected to work independently while maintaining close alignment with cross-functional stakeholders and site procedures.· Occasional support outside standard working hours or travel may be required depending on manufacturing and technology transfer needs. **Why you should apply*** You will help patients in their fight against serious diseases* You will be part of a company that encourages excellence and innovation, respects diversity, develops leaders and values its employees.* You’ll get a competitive salary and a great benefits package including, but not only, an annual bonus, pension contribution, family health insurance, 27 days of annual leave , access to BMS Cruiserath on-site gym and life assurance We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.**How We Work**Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working. **Supporting People with Disabilities**BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. **Candidate Rights**BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/ For roles based in Washington State only: If you live in or expect to work from Washington State if hired for this position, please visit this page for important information about the Washington Fair Chance Act. **Data Protection**We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.If this posting is missing required information required by local law or incorrect, contact BMS at [e-mail] with the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.R1607862 : Senior Scientist, Manufacturing - Process Development