Senior Scientist (Cellular Pharmacology)

ZipRecruiter; England; On-site; GBP 41,000 - 47,000; Full time

Job summary

An established industry player is seeking a Senior Scientist in Cellular Pharmacology to join their innovative Drug Discovery team. This role offers the chance to contribute to groundbreaking cancer research by designing and developing cellular assays that inform drug efficacy. The ideal candidate will possess a strong background in drug discovery and pharmacology, with proficiency in various assay technologies. The organization promotes a supportive environment for personal and professional growth, emphasizing work-life balance and well-being. If you're passionate about making a difference in cancer treatment, this is the perfect opportunity for you.

Benefits

Up to 12% pension contribution

Income protection

Flexible working requests

Comprehensive benefits package

Qualifications

• Experience in drug discovery and characterizing targets.
• Strong understanding of pharmacology and drug-target interactions.
• Proficiency in various quantitative cell assay technologies.

Responsibilities

• Design and run cellular assays to profile small molecules.
• Drive innovation in cellular pharmacology techniques.
• Collaborate with partners to advance cancer targets.

Skills

Drug Discovery

Quantitative Cell Biology

Pharmacology

Assay Development

Liquid Handling and Automation

Education

BSc in Biological Sciences

MSc in Biological Sciences

PhD in Biological Sciences

Tools

ELISA

HTRF

NanoBRET

High Content Imaging

Flow Cytometry

Job description

Job Description

200 staff. Limitless Potential. One team - Cancer Research Horizons.

Senior Scientist - Cellular Pharmacology

Under the leadership of: Agnes Martin

Salary: £41,700 - £46,500 per annum (dependent on experience) plus benefits (includes up to 12% pension contribution and income protection)

Reports to: Principal Scientist, Mechanistic Pharmacology

Department: Research and Innovation

Contract: Permanent

Hours: Full time 35 hours per week (flexible working requests considered if they meet business needs)

Location: Babraham Research Campus, Cambridge

Closing date: 8 May 2025 23:55

This vacancy may close earlier if a high volume of applications is received or once a suitable candidate is found. We recommend applying early. If you require more time due to a reasonable adjustment, please contact us.

Visa Sponsorship: Cancer Research UK can consider visa sponsorship. Please indicate this on your application if applicable.

Recruitment Process: 1st Stage: Screening call via Microsoft Teams; 2nd Stage: in-person interview at Babraham, including competency questions and a case study, sent in advance.

Interview dates: W/C 19 May 2025 (screening), W/C 26 May and 2 June 2025 (interviews)

At Cancer Research UK, we exist to beat cancer.

We have an opportunity within our Drug Discovery team for an experienced and passionate Senior Scientist to contribute scientific expertise to the design, prosecution, and analysis of cellular assays, including bespoke mechanistic data and compound profiling.

About CRUK Drug Discovery

As the world's largest medical research charity, we've helped bring eleven new cancer drugs to market. Our goal is to develop more effective treatments faster. We recently created Cancer Research Horizons (CRH), uniting our drug discovery teams to leverage our pipeline of cancer biology expertise, academic network, cutting-edge technology, and clinical insight to accelerate cancer treatment development.

Based across Cambridge, Glasgow, London, and Newcastle, CRH employs approximately 200 staff from industrial and academic backgrounds.

Our strategy emphasizes deep mechanistic understanding at the molecular and cellular levels throughout project stages, from idea to pre-clinical candidate.

What will I be doing?

This role focuses on designing, developing, and running cellular assays to identify, profile, and characterize small molecules' SAR/SKR, and their mechanisms of action to inform dose prediction and clinical efficacy. You will drive innovation by staying current with cellular pharmacology techniques, contribute to process improvements, and collaborate with partners to advance cancer targets towards patient benefit.

What skills will I need?

We seek an accomplished scientist with:

• A BSc, MSc, or PhD in biological sciences; relevant experience may substitute for formal education
• Significant experience in drug discovery, especially in characterizing targets and modulation by small molecules via quantitative cell biology
• Strong understanding of pharmacology and drug-target interactions
• Proficiency in assay development across various quantitative cell assay technologies (e.g., proliferation, ELISA, HTRF, NanoBRET, high content imaging, reporter assays, 3D colony formation, IncuCyte, MSD, alphaLISA, spheroids, flow cytometry)
• Experience with liquid handling and automation is advantageous

Our organization values

Bold: Act with ambition, courage, and determination

Credible: Act with rigour and professionalism

Human: Act to positively impact people

Together: Act inclusively and collaboratively

We seek individuals who embody these values to help us beat cancer.

What will I gain?

We offer a supportive environment for wellbeing, career development, and personal growth, with a comprehensive benefits package. Our policies promote work-life balance and personal wellbeing. Explore our benefits on our careers webpage.

How do I apply?

We use anonymized shortlisting to promote equality. CVs are required for all applications but will only be reviewed if you are shortlisted for interview. Please complete the work history section of the online form for fair assessment.

For more information, visit our website or contact us. Follow us on LinkedIn, Facebook, Instagram, X, and YouTube for updates.