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Postdoctoral Research Associate in the Molecular Biology of Carbon Dioxide Sensing
Institute for Medical Humanities, Durham University
North East
On-site
GBP 38,000 - 46,000
Full time
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Job summary
An established institution is seeking a Postdoctoral Research Associate to explore the molecular biology of carbon dioxide sensing. This role offers a unique opportunity to engage in groundbreaking research that addresses critical biological processes. You will work in a dynamic and interdisciplinary environment, collaborating with leading experts to advance knowledge in this vital area. With a competitive salary and generous benefits, this position is perfect for those looking to make a significant impact in the field of biosciences while developing their professional skills in a supportive academic setting.
Benefits
Qualifications
- PhD or nearing completion in relevant biological sciences.
- Experience in high-quality academic research and publication.
Responsibilities
- Conduct individual and collaborative research projects.
- Prepare and deliver presentations on research outputs.
- Publish high-quality research papers in peer-reviewed journals.
Skills
Education
Job description
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Join to apply for the Postdoctoral Research Associate in the Molecular Biology of Carbon Dioxide Sensing role at Institute for Medical Humanities, Durham University
Postdoctoral Research Associate in the Molecular Biology of Carbon Dioxide Sensing (
Job Number:
25000536)
Department of Biosciences
Grade 7: - £38,249 - £45,413 per annum
Fixed Term - Full Time
Contracted Hours per Week: 35
Closing Date
: 01-Jun-2025, 10:59:00 PM
Disclosure and Barring Service Requirement: Not Applicable.
Working at Durham University
A globally outstanding centre of teaching and research excellence, a warm and friendly place to work, a unique and historic setting – Durham is a university like no other.
As one of the UK’s leading universities, Durham is an incredible place to define your career.The University is located within a beautiful historic city, home to a UNESCO World Heritage Site, and surrounded by stunning countryside. Our talented scholars and researchers from around the world are tackling global issues and making a difference to people's lives.
We believe that inspiring our people to do outstanding things at Durham enables Durham people to do outstanding things in the world. Being a part of Durham is about more than just the success of the University, it’s also about contributing to the success of the city, county and community.
Our University Strategy is built on three pillars of research, education and wider student experience, but also on our keen sense of community and of inspiring others to achieve their potential.
Our Purpose and Values
We want our University to be a place where people can be free to be themselves, no matter what their identity or background. Together, we celebrate difference, value one another and are each responsible for creating an inclusive community that is respectful and fair for all.
Find out more about the benefits of working at the University and what it is like to live and work in the Durham area on our Why Join Us? - Information Page
The Department
Biosciences is one of the very best departments in the UK with an outstanding reputation for excellence in teaching, research and employability of our students. The department provides a dynamic and interdisciplinary research environment, with the Cann group located within bespoke laboratories for interdisciplinary work at the biology-chemistry interface
The Role
The identification of carbon dioxide-binding proteins
Carbon dioxide is essential for life. It is at the beginning of every life process as a fundamental substrate of photosynthesis or chemosynthesis and is at the end of every life process as the product of aerobic respiration and post-mortem decay. As such, it is not a surprise that this gas regulates such diverse processes as cellular chemical reactions, transport, maintenance of the cellular environment, behaviour and immunity. Carbon dioxide is a strategically important research target with relevance to crop responses to environmental change, insect-borne disease and public health. However, we know very little of the direct interactions of carbon dioxide with the cell, despite the importance of the gas to biology.
Carbon dioxide mediates the earliest known example of a protein post-translational modification (PTM), identified on haemoglobin in 1928. Carbon dioxide can directly combine with select protein groups to form carbamates. Influential research programmes from the 1920-80's demonstrated that the carbamate PTM regulates oxygen-binding in haemoglobin and activates the carbon dioxide-fixing enzyme Rubisco. George Lorimer proposed carbamate PTMs as a mechanism for regulating biological responses to carbon dioxide in 1983. However, the carbamate PTM is unstable outside the cell and its identification presents significant analytical challenges. Several stable carbamates have been identified in protein molecular structures, but the technical difficulties in their widespread identification has resulted in carbon dioxide-mediated carbamylation being all but forgotten as a PTM. For example, the Wikipedia page for PTM does not mention carbon dioxide-mediated carbamylation (not to be confused with the similarly named modification mediated by isocyanic acid) among 61 identified PTMs.
Direct protein targets for carbon dioxide sensing are almost completely unknown. We have developed technology to systematically identify carbon dioxide-binding proteins. We propose to understand the mechanism by which insect chemosensory receptors are able to sense and respond to carbon dioxide. The research programme will provide broad insight into direct molecular responses to carbon dioxide and supply tools that will revolutionise our understanding of carbon dioxide biology. The wrok will be perform in collaboration with colleagues at Warwick University.
The position offers an exciting opportunity to develop interdisciplinary skills in biosciences and the physical sciences in an entirely new area of biology.
The post is fixed term for 6 months and the successful candidate will be working with Prof Martin Cann (PI; Dept of Biosciences) at Durham University.
Responsibilities :
- To understand and convey material of a specialist or highly technical nature to the team or group of people through presentations and discussions that leads to the presentation of research papers in conferences and publications.
- To prepare and deliver presentations on research outputs/activities to audiences which may include: research sponsors, academic and non-academic audiences.
- To publish high quality outputs, including papers for submission to peer reviewed journals and papers for presentation at conferences and workshops under the direction of the Principal Investigator or Grant-holder.
- To assist with the development of research objectives and proposals.
- To conduct individual and collaborative research projects under the direction of the Principal Investigator or Grant-holder.
- To work with the Principal Investigator or Grant-holder and other colleagues in the research group, as appropriate, to identify areas for research, develop new research methods and extend the research portfolio.
- To deal with problems that may affect the achievement of research objectives and deadlines by discussing with the Principal Investigator or Grant-holder and offering creative or innovative solutions.
- To liaise with research colleagues and make internal and external contacts to develop knowledge and understanding to form relationships for future research collaboration.
- To plan and manage own research activity, research resources in collaboration with others and contribute to the planning of research projects.
- To deliver training in research techniques/approaches to peers, visitors and students as appropriate.
- To be involved in student supervision, as appropriate, and assist with the assessment of the knowledge of students.
- To contribute to fostering a collegial and respectful working environment which is inclusive and welcoming and where everyone is treated fairly with dignity and respect.
- To engage in wider citizenship to support the department and wider discipline.
- To engage in continuing professional development by participation in the undergraduate or postgraduate teaching programmes or by membership of departmental committees, etc. and by attending relevant training and development courses.
Successful applicants will be in post by October 1st 2025.
The post-holder is employed to work on research/a research project which will be led by another colleague. Whilst this means that the post-holder will not be carrying out independent research in his/her own right, the expectation is that they will contribute to the advancement of the project, through the development of their own research ideas/adaptation and development of research protocols.
Working at Durham
A competitive salary is only one part of the many fantastic benefits you will receive if you join the University: you will also receive access to the following fantastic benefits:
- 30 Days annual leave per year in addition to 8 public holidays and 4 customary days per year – a total of 42 days per year.
- The University closes between Christmas and New Year – please include or delete if not applicable.
- We offer a generous pension scheme, As a new member of staff you will be automatically enrolled into the University Superannuation Scheme (USS).
- No matter how you travel to work, we have you covered. We have parking across campus, a cycle to work scheme which helps you to buy a bike and discount with local bus and train companies.
- There is a genuine commitment to developing our colleagues professionally and personally. There is a comprehensive range of development courses, apprenticeships and access to qualifications and routes to develop your career in the University. All staff have dedicated annual time to concentrate on their personal development opportunities.
- Lots of support for health and wellbeing including discounted membership for our state of the art sport and gym facilities and access to a 24-7 Employee Assistance Programme.
- On site nursery is available plus access to holiday camps for children aged 5-16.
- Family friendly policies, including maternity and adoption leave, which are among the most generous in the higher education sector (and likely above and beyond many employers).
- The opportunity to take part in staff volunteering activities to make a difference in the local community
- Discounts are available via our benefits portal including; money off at supermarkets, high street retailers, IT products such as Apple, the cinema and days out at various attractions.
- A salary sacrifice scheme is also available to help you take advantage of tax savings on benefits.
- If you are moving to Durham, you may be eligible for help with removal costs and we have a dedicated team who can help you with the practicalities such as house hunting and schools. If you need a visa, we cover most visa costs and offer an interest free loan scheme to pay for dependant visas.
Durham University is committed to equality, diversity and inclusion
Equality, diversity, and inclusion (EDI) are a key component of the University’s Strategy and a central part of everything we do. We also live by our Purpose and Values and our Staff Code of Conduct. At Durham we actively work towards providing an environment where our staff and students can study, work and live in a community which is supportive and inclusive. It’s important to us that all colleagues undertake activities that are aligned to both our values and commitment to EDI.
We welcome and encourage applications from those who are currently under-represented in our work force, including people with disabilities and from racially minoritised ethnic groups.
If you have taken a career break or periods of leave that may have impacted on the volume and recency of your research outputs and other activities, such as maternity, adoption or parental leave, you may wish to disclose this in your application. The selection committee will take this into account when evaluating your application.
The University has been awarded the Disability Confident Leader status. If you are a candidate with a disability, we are committed to ensuring fair treatment throughout the recruitment process. We will make adjustments to support the interview process wherever it is reasonable to do so and, where successful, reasonable adjustments will be made to support people within their role.
Person Specification
Essential:
The Requirements
Qualifications
- A good first degree in biological sciences or chemistry.
- A PhD in molecular bioscience or biochemistry OR be close to be being awarded.
- Experience in conducting high quality academic research.
- Demonstrable ability to write material of a quality commensurate with publication in highly-ranked journals.
- Demonstrable ability to present research papers at international conferences and communicate complex information to specialists and within the wider academic community.
- Experience in proteomics or in vitro biochemistry.
- Experience in recombinant protein production.
- Experience in molecular biology.
- Demonstrable ability to work cooperatively as part of a team, including participating in research meetings.
- Ability to work independently on own initiative and to strict deadlines.
- Excellent interpersonal and communication skills.
Experience
- Strong publication record in peer-reviewed journals, commensurate with stage of career.
- A track record of presenting research at conferences, symposia, or meetings, commensurate with stage of career.
- Demonstrable ability to develop research proposals and designs in collaboration with other academics.
- Experience of overseeing students with respect to the development of their practical/research skills e.g. acting as a demonstrator; supervising student projects/practicals.
- Experience in carbon dioxide in biological systems
- Demonstrable ability to plan and manage independent research.
For informal enquiries please contact Prof Martin Cann [m.j.cann@durham.ac.uk]. All enquiries will be treated in the strictest confidence.
Contact information for technical difficulties when submitting your application
If you encounter technical difficulties when using the online application form, we prefer you send enquiries by email. Please send your name along with abrief description of the problem you’re experiencing toe.recruitment@durham.ac.uk
Alternatively, you may call 0191 334 6801 from the UK, or +44 191 334 6801 from outside the UK. This number operates during the hours of 09.00 and 17.00 Monday to Friday, UK time. We will normally respond within one working day (Monday to Friday, excluding UK public holidays).
How To Apply
University contact for general queries about the recruitment process
To progress to the assessment stage, candidates must evidence each of the essential criteria required for the role in the person specification below. It will be at the discretion of the recruiting panel as to whether they will also consider any desirable criteria, but we would urge candidates to provide evidence for all criteria.
While some criteria will be considered at the shortlisting stage, other criteria may be considered later in the assessment process, such as questions at interview.
Submitting your application
We prefer to receive applications online. We will update you about your application at various points throughout the selection process, via automated emails from our e-recruitment system. Please check your spam/junk folder periodically to make sure you have not missed any of our updates.
What To Submit
All applicants are asked to submit:
- a CV and cover letter which details your experience, skills, and achievements in meeting (or the potential to meet) the criteria set out below.
- Any other additional documents the department feel would support the shortlisting process
Short-listed candidates will be invited to the University, either virtually or in-person and will have the opportunity to meet key members of the Department. The assessment for the post will normally include [a presentation to staff and students in the Department followed by an interview] and we anticipate that the assessments and interviews will take place over two days in or around [DATE].
In the event that you are unable to attend in person on the date offered, it may not be possible to offer you an interview on an alternative date.
Please note that in submitting your application Durham University will be processing your data. We would ask you to consider the relevant University Privacy Statement Job Applicants/Potential Job Applicants - Durham University which provides information on the collation, storing and use of data.
When appointing to this role the University must ensure that it meets any applicable immigration requirements, including salary thresholds which are applicable to some visas.
- Seniority levelInternship
- Employment typeFull-time
- Job functionResearch, Analyst, and Information Technology
- IndustriesHigher Education
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