iPSC & CRISPR Cell Line Scientist – London

Substrate Bio Ltd; Greater London; In loco; GBP 55.000 - 85.000; Tempo pieno

Vantaggi offerti da questo lavoro

30 days annual leave

Pension with 10% employer contribution

Top-tier Bupa private health cover

Descrizione del lavoro

Substrate Bio Ltd in London is seeking a careful hands-on cell biologist to own the cell lines behind our screening pipelines. You will culture iPSCs and other demanding cells, perform CRISPR edits, and generate clonal lines with thorough documentation.

You will differentiate iPSCs into neurons and other lineages, validate them by genotyping and QC, and build banked stocks with traceable histories to support automated workflows.

Competenze

• PhD or MSc with hands-on experience culturing iPSCs or other demanding cells.
• Practical CRISPR genome editing and clonal line generation.
• Excellent aseptic technique and careful, traceable record-keeping.

Mansioni

• Culture human iPSCs and other demanding cells with rigorous record-keeping.
• Perform CRISPR edits and generate clonal lines.
• Differentiate iPSCs into neurons and other lineages; validate by genotyping and QC.
• Build and manage cell banks with traceable histories for automated workflows.

Conoscenze

Cell culture

iPSC handling

CRISPR editing

Genotyping

Record-keeping

Formazione

PhD in cell biology

MSc in a related field

Strumenti

PCR

Sanger sequencing

NGS

Descrizione del lavoro

Substrate Bio Ltd in London is seeking a careful hands-on cell biologist to own the cell lines behind our screening pipelines. You will culture iPSCs and other demanding cells, perform CRISPR edits, and generate clonal lines with thorough documentation.

You will differentiate iPSCs into neurons and other lineages, validate them by genotyping and QC, and build banked stocks with traceable histories to support automated workflows.