In Vivo Neuroscience Scientist — Longitudinal 2P Imaging

Convergent Research; Greater London; On-site; GBP 60,000 - 75,000; Full time

Job summary

Meridial seeks an experienced Scientist – In Vivo Neuroscience to establish and run advanced in vivo experiments, including neuroimaging and optogenetics in mice. You will develop protocols, train team members and work closely with engineers and computational researchers to ensure high-quality data and rigorous methods.

You will report to the Director of Experimental Research and contribute to platform development, experimental quality control and longitudinal study design.

Qualifications

• PhD in neuroscience, neurobiology, physiology, neuroengineering or related field or equivalent experience.
• 5+ years’ experience performing in vivo two-photon microscopy in mice with survival stereotaxic surgery and chronic cranial-window preparations.
• Ability to develop and improve experimental methods and translate questions into robust designs.

Responsibilities

• Perform complex in vivo neurosurgery and longitudinal two-photon imaging in mice.
• Design and run optogenetic experiments to interrogate neural circuits.
• Oversee animal welfare and colony management for longitudinal studies.
• Develop detailed protocols, SOPs and workflows for imaging and surgery.
• Collaborate with engineering and data teams to integrate experiments and open data standards.

Skills

In vivo two-photon imaging

Python/MATLAB

Mentoring

Experimental design

Education

PhD in neuroscience or related field

Tools

Two-photon microscopy

Stereotaxic surgery

Intracranial viral injections

Chronic cranial-window prep

Job description

Meridial seeks an experienced Scientist – In Vivo Neuroscience to establish and run advanced in vivo experiments, including neuroimaging and optogenetics in mice. You will develop protocols, train team members and work closely with engineers and computational researchers to ensure high-quality data and rigorous methods.

You will report to the Director of Experimental Research and contribute to platform development, experimental quality control and longitudinal study design.