Bioanalytical Method Development Lead — LCMS/MS

Nexus Life Sciences

Plymouth

On-site

GBP 50,000 - 60,000

Full time

4 days ago
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Job summary

Nexus Life Sciences in Plymouth, UK, is seeking an MS Method Development Lead to drive development and validation of LCMSMS bioanalytical methods under GxP standards. This role blends technical excellence with team leadership.

You will optimise extraction and chromatography, mentor the Method Development & Validation team, ensure GLP compliance, support regulatory submissions, and lead continuous improvement in a cutting-edge bioanalytical lab.

Qualifications

  • Degree in Biochemistry, Biomedical Science, or related field.
  • 4+ years in a GxP laboratory with at least 2+ years in management.
  • Proven expertise in HPLC/UPLC and LCMSMS method development and validation.
  • Strong knowledge of GLP, SOPs, and regulatory requirements.

Responsibilities

  • Lead method development and validation as a subject matter expert.
  • Optimise extraction, chromatography, and LC methods.
  • Manage and mentor the Method Development & Validation team.
  • Ensure GLP compliance and adherence to SOPs.
  • Support regulatory submissions and respond to queries.
  • Drive continuous improvement and CAPA processes.
  • Prepare, review, and transfer validated methods to analytical teams.

Skills

GxP laboratory experience
HPLC
UPLC
LCMSMS
Chromatography data systems
Method development & validation
Problem solving
Regulatory and GLP knowledge
Leadership and mentoring

Education

Degree in Biochemistry, Biomedical Science, or related field

Tools

Empower
MassLynx
Minitab

Job description

Nexus Life Sciences in Plymouth, UK, is seeking an MS Method Development Lead to drive development and validation of LCMSMS bioanalytical methods under GxP standards. This role blends technical excellence with team leadership.

You will optimise extraction and chromatography, mentor the Method Development & Validation team, ensure GLP compliance, support regulatory submissions, and lead continuous improvement in a cutting-edge bioanalytical lab.

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