Postdoc in Chromosome Biology & Genome Regulation

PSL Research University; Paris; On-site; EUR 36,000 - 40,000; Full time

Benefits offered by this job

Collective catering

75% transportation reimbursement

Supplementary health insurance

Job summary

The Curie Institute Research Center in Paris seeks a highly motivated researcher to join the GeneMotors program. You will develop quantitative models of genome regulation and test them with experimental data, focusing on cohesin-mediated loop extrusion and long-range gene regulation.

The role involves close collaboration with computational and experimental teams, contributing to publications, and working in an international environment. A fixed-term, full-time contract is offered in Paris.

Qualifications

• PhD in Biology, Physics or Biophysics.
• Fluency in English required (English is the working language of the team).
• Experience with quantitative analyses of biological datasets (genomics, transcription, or imaging).

Responsibilities

• Develop sister-resolved Hi‑C protocols and obtain Hi‑C data for centromeres.
• Obtain super-resolution microscopy data of centromere organization and chromosome translocations.
• Quantitatively analyze genomic, Hi‑C, and imaging data to test models of centromere and chromosome organization.
• Work with computational and experimental collaborators to iteratively refine physical predictions.
• Contribute to scientific publications and presentations within an international consortium.

Skills

Chromosome biology

Hi-C techniques

Genomic data analysis

Interdisciplinary collaboration

Education

PhD in Biology/Physics/Biophysics

Bac+6 et plus

Job description

The Curie Institute Research Center in Paris seeks a highly motivated researcher to join the GeneMotors program. You will develop quantitative models of genome regulation and test them with experimental data, focusing on cohesin-mediated loop extrusion and long-range gene regulation.

The role involves close collaboration with computational and experimental teams, contributing to publications, and working in an international environment. A fixed-term, full-time contract is offered in Paris.