Postdoc in Cellular Biophysics & Electroporation Modeling

CNRS - National Center for Scientific Research; France; On-site; EUR 32,000 - 42,000; Full time

Job summary

The postdoctoral researcher will join the DEVIN project at IPBS (Toulouse) within the Cellular Biophysics team to explore DNA electropermeabilization and membrane interactions using experimental and numerical modeling approaches.

The role combines GUV preparation, electroporation experiments, fluorescence microscopy, and data-driven comparisons with COMSOL-based models, culminating in publications and dissemination of results.

Qualifications

• PhD in biophysics, applied physics, biomedical engineering, or related discipline.
• Postdoctoral experience in cell biology and fluorescence microscopy.
• Experience with electroporation and membrane biophysics.
• Programming in Python; image analysis with ImageJ/Fiji.

Responsibilities

• Prepare and characterize giant unilamellar vesicles (GUVs).
• Perform electroporation experiments on lipid membranes and cultured cells.
• Investigate membrane permeabilization, morphological changes and lipid peroxidation.
• Culture adherent cells and conduct plasmid DNA transfer experiments.
• Use optical/fluorescence microscopy and quantitative image analysis.
• Process experimental data and compare with numerical models.
• Present research findings and write scientific publications.

Skills

Cell biology

Fluorescence microscopy

Python programming

ImageJ/Fiji

Electroporation

Biophysics

GUV preparation

Education

PhD in biophysics, applied physics, biomedical engineering, or related discipline

Tools

COMSOL Multiphysics

ImageJ/Fiji

Job description

The postdoctoral researcher will join the DEVIN project at IPBS (Toulouse) within the Cellular Biophysics team to explore DNA electropermeabilization and membrane interactions using experimental and numerical modeling approaches.

The role combines GUV preparation, electroporation experiments, fluorescence microscopy, and data-driven comparisons with COMSOL-based models, culminating in publications and dissemination of results.