Research asscociate/ Doctoral candidate (m/w/d) for the project \"The function of tumour-associated neutrophils on the spontaneous regression of colon polyps\"

Technische Universität München (Technical University of Munich); München; In loco; EUR 20.000 - 30.000; Part-time

Vantaggi offerti da questo lavoro

DFG funded PhD

TV-L E13 (65%)

Descrizione del lavoro

PhD position in tumor immunology is available at Technische Universität München (TUM) in the School of Life Sciences – Infection Pathogenesis. The project investigates TANs in polyp dynamics using a pig model and organoid–neutrophil co-culture systems.

The successful candidate will work in an interdisciplinary environment, perform in vivo and in vitro studies, and contribute to manuscripts. TV-L E13 (65%), three-year position, with German Research Foundation (DFG) funding.

Competenze

• Master’s degree or Staatsexamen or equivalent in Veterinary Medicine, Animal sciences, Medicine, Biology, Biotechnology or related fields.
• Ability to work independently as well as collaboratively in an international team.
• Very good written and spoken English; strong analysis and problem-solving capacities.
• Experience with molecular biology, flow cytometry, immunohistochemistry, cell culture, or animal models is advantageous.

Mansioni

• Plan and conduct experimental studies investigating TAN phenotypes and functions during intestinal polyp development.

Conoscenze

Independence & teamwork

English fluency

Analytical thinking

Lab techniques awareness

Interdisciplinary collaboration

Formazione

Master’s degree or Staatsexamen or equivalent in Veterinary Medicine, Animal Sciences, Medicine, Biology, Biotechnology

Strumenti

Molecular biology

Flow cytometry

Immunohistochemistry

Cell culture

Animal models

Descrizione del lavoro

PhD position in tumor immunology

Research asscociate/ Doctoral candidate (m/w/d) for the project "The function of tumour-associated neutrophils on the spontaneous regression of colon polyps"

30.09.2026, Academic staff

We are seeking a highly motivated PhD candidate (E13, 65%) to join a DFG-funded research project investigating the role of tumor-associated neutrophils (TANs) in intestinal polyp dynamics in a pig model.

The Chair for Infection Pathogenesis is looking for academic staff, starting as soon as possible.

Background

We are seeking a highly motivated PhD candidate (E13, 65%) to join a DFG-funded research project investigating the role of tumor-associated neutrophils (TANs) in intestinal polyp dynamics in a pig model. The pig model provides an excellent opportunity to explore the diverse facets of comparative immunology and to bridge fundamental immunological mechanisms with translational research.

This project aims to elucidate the function of TANs on polyp growth and regression with a particular focus on their interaction with the local tissue microenvironment and immune response. A key component of the project will be the establishment and use of intestinal organoid–neutrophil co‑culture models to study TAN‑mediated effects on epithelial and polyp cells. The successful candidate will work in an interdisciplinary research environment using state‑of‑the‑art molecular, cellular, immunological, and organoid-based approaches.

Your responsibilities

The successful candidate will plan and conduct experimental studies investigating TAN phenotypes and functions during intestinal polyp development. The work combines in vivo studies using transgenic animal models, including animal breeding, sample collection, and histopathological analyses, with in vitro organoid–immune cell co‑culture systems and molecular, cellular and immunological assays. The candidate will analyze and interpret the resulting data, present findings at scientific meetings, and contribute to manuscripts and reports. Independent experimental work, careful sample handling, and a high level of scientific responsibility are expected.

Your Qualifications, Key Skills And Experience

• Master’s degree or Staatsexamen or equivalent in Veterinary Medicine, Animal sciences, Medicine, Biology, Biotechnology or related fields
• Ability to work independently as well as collaboratively in an international team
• Strong interest in tumour immunology, inflammation, and gastrointestinal disease
• Experience with molecular biology, flow cytometry, immunohistochemistry, cell culture, or animal models is advantageous
• Very good written and spoken English, Strong analysis and problem-solving capacities

What We Offer

The candidate will have the opportunity to work in an interdisciplinary and international scientific environment. Research staff is supported by easy access to scientific expertise, well‑equipped lab and core facilities and an active science community @Weihenstephan Campus. We offer a three‑year PhD position funded by the German Research Foundation (DFG) and an employment according to TV‑L E13 (65%).

The position is suitable for disabled persons. Disabled applicants will be given preference in case of generally equivalent suitability, aptitude and professional performance.

Technische Universität München

School of Life Sciences – Infection Pathogenesis

Prof. Dr. rer. nat. Friederike Ebner

Liesel-Beckmann-Str. 1, 80333 Freising

Kontakt: [e-mail]

More Information

https://www.mls.ls.tum.de/ipat/offene-stellen/#c10079