PhD Position (E13, 65%) in Tumor Immunology

Technische Universität München Verwaltungsstelle Weihenst; Freising; On-site; EUR 12,000 - 18,000; Part time

Job summary

The Chair for Infection Pathogenesis at Technische Universität München invites applications for a PhD position (E13, 65%) to study tumor-associated neutrophils in intestinal polyp dynamics using a pig model and organoid–neutrophil co-cultures.

The project combines in vivo breeding, sample collection, histopathology, and in vitro assays in an interdisciplinary environment; funding is provided by DFG and TV-L E13 (65%).

Qualifications

• Master’s degree or equivalent in a life-science field.
• Ability to work independently and in international teams.
• Strong interest in tumour immunology, inflammation, and gastrointestinal disease.

Responsibilities

• Plan and conduct experimental studies investigating TAN phenotypes and functions during intestinal polyp development.
• Perform in vivo studies using transgenic animal models, including breeding, sample collection, and histopathological analyses.
• Use in vitro organoid–immune cell co‑culture systems and molecular, cellular and immunological assays.

Skills

Independent work

Team collaboration

English proficiency

Analytical skills

Molecular biology techniques

Flow cytometry

Immunohistochemistry

Cell culture

Animal models experience

Education

Master’s degree or Staatsexamen or equivalent in Veterinary Medicine, Animal sciences, Medicine, Biology, Biotechnology or related fields

Job description

PhD Position (E13, 65%) in Tumor Immunology

The Chair for Infection Pathogenesis is looking for academic staff, starting as soon as possible.

Background

We are seeking a highly motivated PhD candidate (E13, 65%) to join a DFG-funded research project investigating the role of tumor-associated neutrophils (TANs) in intestinal polyp dynamics in a pig model. The pig model provides an excellent opportunity to explore the diverse facets of comparative immunology and to bridge fundamental immunological mechanisms with translational research.

This project aims to elucidate the function of TANs on polyp growth and regression with a particular focus on their interaction with the local tissue microenvironment and immune response. A key component of the project will be the establishment and use of intestinal organoid–neutrophil co‑culture models to study TAN‑mediated effects on epithelial and polyp cells. The successful candidate will work in an interdisciplinary research environment using state‑of‑the‑art molecular, cellular, immunological, and organoid‑based approaches.

Your responsibilities

The successful candidate will plan and conduct experimental studies investigating TAN phenotypes and functions during intestinal polyp development. The work combines in vivo studies using transgenic animal models, including animal breeding, sample collection, and histopathological analyses, with in vitro organoid–immune cell co‑culture systems and molecular, cellular and immunological assays. The candidate will analyse and interpret the resulting data, present findings at scientific meetings, and contribute to manuscripts and reports. Independent experimental work, careful sample handling, and a high level of scientific responsibility are expected.

Your qualifications, key skills and experience

• Master’s degree or Staatsexamen or equivalent in Veterinary Medicine, Animal sciences, Medicine, Biology, Biotechnology or related fields
• Ability to work independently as well as collaboratively in an international team
• Strong interest in tumour immunology, inflammation, and gastrointestinal disease
• Experience with molecular biology, flow cytometry, immunohistochemistry, cell culture, or animal models is advantageous
• Very good written and spoken English,Strong analysis and problem‑solving capacities

What we offer

The candidate will have the opportunity to work in an interdisciplinary and international scientific environment. Research staff is supported by easy access to scientific expertise, well‑equipped lab and core facilities and an active science community @Weihenstephan Campus. We offer a three‑year PhD position funded by the German Research Foundation (DFG) and an employment according to TV‑L E13 (65%).

Technische Universität München

School of Life Sciences – Infection Pathogenesis

Prof. Dr. rer. nat. Friederike Ebner

Liesel‑Beckmann‑Str.1,80333Freising

[e-mail]

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