Senior Bioprocess Engineer, Biotech GMP Scale-Up

Placements24; Polokwane; Hybrid; ZAR 1,200,000 - 1,800,000; Full time

Benefits offered by this job

Competitive salary package

Health insurance

Retirement fund contributions

Paid time off

Professional development opportunities

State-of-the-art facility

Job summary

Placements24 seeks a Senior Process Engineer to optimize and scale bioprocesses for biopharmaceutical production in Polokwane, Limpopo. The role focuses on design, troubleshooting, and transfer of processes for novel therapeutics, with a strong GMP framework driving development across R&D and manufacturing teams.

The ideal candidate has 6+ years in biopharma process development, expertise in fermentation, cell culture, and downstream purification, and excellent problem-solving and leadership

Qualifications

• Master's or Ph.D. in Biochemical/ Chemical Engineering or related field.
• Minimum 6 years in biopharma process development and manufacturing.
• Experience with fermentation, cell culture, and downstream purification."
• Strong GMP knowledge and CAPA experience.

Responsibilities

• Design, develop, and optimize bioprocesses for fermentation and cell culture, ensuring scalability and robustness.
• Oversee downstream purification processes, including chromatography, filtration, and ultrafiltration.
• Develop and execute process validation protocols, ensuring GMP compliance.
• Lead process transfer activities from development to manufacturing scale.
• Conduct process hazard analyses and implement safety measures.
• Collaborate with R&D, QA, and Manufacturing to ensure seamless integration of processes.
• Mentor junior engineers and provide technical guidance.

Skills

Bioprocess engineering

Process scale-up

GMP compliance

Cross-functional leadership

Problem solving

Education

Master's or Ph.D. in Biochemical/ Chemical Engineering

Tools

Process simulation software

Job description

Placements24 seeks a Senior Process Engineer to optimize and scale bioprocesses for biopharmaceutical production in Polokwane, Limpopo. The role focuses on design, troubleshooting, and transfer of processes for novel therapeutics, with a strong GMP framework driving development across R&D and manufacturing teams.

The ideal candidate has 6+ years in biopharma process development, expertise in fermentation, cell culture, and downstream purification, and excellent problem-solving and leadership