Senior Analytical Chemist - Pharmaceutical QA/QC

Placements24; Mbombela (Nelspruit); On-site; ZAR 900,000 - 1,200,000; Full time

Benefits offered by this job

Annual bonus potential

Medical benefits

Retirement plan

Paid time off

Training and development

Growth opportunities

Job summary

Placements24 is seeking a Senior Analytical Chemist for a reputable pharmaceutical manufacturer in Nelspruit. You will drive analytical method development, validation, and transfer, using HPLC, GC, and UV-Vis techniques to ensure product quality and regulatory compliance.

The role requires hands-on instrument work, data review, CAPA investigations, and adherence to GMP/ICH guidelines, with opportunities for career growth in QA/QC.

Qualifications

• Bachelor's or Master's degree in Chemistry, Pharmaceutical Sciences, or related field.
• Minimum 6 years of analytical chemistry experience in pharmaceutical QA/QC.
• Strong GMP/ICH knowledge and method validation experience.

Responsibilities

• Perform quantitative/qualitative analysis of materials and finished products.
• Develop, validate, and transfer analytical methods (HPLC/GC/UV-Vis).
• Operate and maintain analytical instruments with proper calibration.
• Review data, test results, and batch release documentation.
• Investigate OOS results and implement CAPA actions.
• Ensure compliance with GMP and regulatory guidelines.

Skills

HPLC

GC

UV-Vis

Dissolution

Method validation

CAPA

GMP

ICH guidelines

Data review

Education

Bachelor's in Chemistry

Master's in Pharmaceutical Sciences

Tools

HPLC systems

GC instruments

Dissolution apparatus

Job description

About the Role

Our client, a reputable pharmaceutical manufacturer in Nelspruit , is seeking a highly skilled Senior Analytical Chemist to join their Quality Assurance and Quality Control (QA/QC) department. This role is crucial for ensuring the quality, safety, and efficacy of pharmaceutical products through rigorous testing and analysis. You will be responsible for developing and validating analytical methods, operating sophisticated instrumentation, and ensuring compliance with stringent regulatory standards. This is a prime opportunity for an experienced analytical chemist to contribute to the pharmaceutical industry's high standards in a key Mpumalanga location.

Key Responsibilities

• Perform quantitative and qualitative analysis of raw materials, in-process samples, and finished pharmaceutical products.
• Develop, validate, and transfer analytical methods using techniques such as HPLC, GC, UV-Vis spectroscopy, and dissolution testing.
• Operate and maintain analytical instruments, ensuring calibration and proper functioning.
• Review and approve analytical data, test results, and batch release documentation.
• Investigate Out-of-Specification (OOS) results and implement corrective and preventive actions (CAPA).
• Ensure compliance with Good Manufacturing Practices (GMP) and other relevant regulatory guidelines.

Requirements

• Bachelor's or Master's degree in Chemistry, Pharmaceutical Sciences, or a related field.
• Minimum of 6 years of experience in analytical chemistry within the pharmaceutical industry, specifically in QA/QC.
• Extensive hands-on experience with HPLC, GC, and other relevant pharmaceutical analytical techniques.
• Thorough understanding of GMP, ICH guidelines, and regulatory requirements for pharmaceutical testing.
• Strong knowledge of method validation principles and execution.
• Excellent analytical, problem-solving, and documentation skills.

Benefits

• Competitive salary with annual bonus potential.
• Comprehensive medical and retirement benefits.
• Generous paid time off and holiday leave.
• Opportunities for training and professional development in pharmaceutical quality control.
• A stable and well-established company with a commitment to employee growth in Nelspruit .