Clinical Operations Manager

Placements24; Noord-Kaap; On-site; ZAR 1,200,000 - 2,100,000; Full time

Benefits offered by this job

Competitive salary package

Medical aid

Retirement savings plan

Life insurance

Professional development

Annual leave

Job summary

Placements24 in Kimberley, Northern Cape, South Africa, seeks an experienced Clinical Operations Manager to lead the clinical operations team and oversee end-to-end trials. The ideal candidate will drive adherence to timelines and budgets while upholding quality and regulatory standards.

You will collaborate with departments such as Data Management, Regulatory Affairs, and Biostatistics, manage vendor relationships, and contribute to business development.

Qualifications

• 7–10 years of experience in clinical operations with at least 3 years in a management role.
• Experience across Phase I–IV clinical trials.
• Strong knowledge of GCP and ICH guidelines and regulatory requirements.
• Excellent leadership, team management and communication skills.

Responsibilities

• Lead and manage the clinical operations department, including project planning, resource allocation, and team development.
• Oversee the execution of multiple clinical trials from initiation through close-out.
• Ensure compliance with GCP, ICH and company SOPs.
• Develop and manage trial budgets and timelines with efficient resource utilization.
• Collaborate with Data Management, Regulatory Affairs, Biostatistics to ensure seamless trial execution.
• Build and maintain relationships with sites, vendors and sponsors.
• Implement process improvements to enhance efficiency and quality.
• Monitor trial progress, identify risks and develop mitigation strategies.
• Recruit, train, and mentor clinical research staff.
• Contribute to business development and proposal development.

Skills

Leadership

Project management

Regulatory knowledge

Communication

Education

Bachelor's degree in science/healthcare

Advanced degree preferred

Tools

CTMS

EDC systems

Job description

About the Role

Our client, a rapidly growing Contract Research Organization (CRO), is seeking an experienced Clinical Operations Manager to lead their team in Kimberley, Northern Cape, ZA . This crucial role will oversee the planning, execution, and completion of clinical trials, ensuring adherence to timelines, budgets, and quality standards. You will manage a team of clinical research professionals, provide strategic direction, and foster a collaborative and high-performance culture. The ideal candidate will possess strong leadership skills, a deep understanding of clinical trial processes, and a commitment to operational excellence. This is a significant opportunity to shape the future of clinical research within a dynamic and expanding organization based in the heart of the Northern Cape .

Key Responsibilities

• Lead and manage the clinical operations department, including project planning, resource allocation, and team development.
• Oversee the execution of multiple clinical trials from initiation through close-out.
• Ensure compliance with all relevant regulatory requirements (GCP, ICH) and company SOPs.
• Develop and manage clinical trial budgets and timelines, ensuring efficient resource utilization.
• Collaborate with internal departments (e.g., Data Management, Regulatory Affairs, Biostatistics) to ensure seamless trial execution.
• Build and maintain strong relationships with investigative sites, vendors, and study sponsors.
• Implement process improvements to enhance the efficiency and quality of clinical trial operations.
• Monitor trial progress, identify risks, and develop mitigation strategies.
• Recruit, train, and mentor clinical research staff.
• Contribute to business development activities and proposal development.

Requirements

• Bachelor's degree in a scientific or healthcare-related field; advanced degree preferred.
• Minimum of 7-10 years of experience in clinical operations within the pharmaceutical or CRO industry, with at least 3 years in a management role.
• Extensive experience in managing all phases of clinical trials (Phase I-IV).
• Proven track record of successfully managing clinical trial budgets and timelines.
• Strong knowledge of GCP, ICH guidelines, and regulatory requirements.
• Excellent leadership, team management, and communication skills.
• Proficiency in Clinical Trial Management Systems (CTMS) and EDC systems.
• Strong analytical and problem-solving abilities.
• Ability to work effectively in a fast-paced, demanding environment.
• Experience in vendor management.

Benefits

• Our client offers a highly competitive salary package, including performance-based bonuses, comprehensive medical aid, a retirement savings plan, and life insurance.
• We provide opportunities for professional development, including leadership training, conference attendance, and support for further education.
• This role is based in our Kimberley office, providing a stable and professional work environment.
• We believe in fostering a healthy work-life balance and offer generous annual leave.
• Join a growing organization that values its employees and is committed to delivering high-quality clinical research services.