Analytical Chemist - Pharmaceutical Development

Placements24; South Africa; Hybrid; ZAR 400,000 - 600,000; Full time

Benefits offered by this job

Hybrid work model

Medical aid

Retirement fund

Performance bonus

Job summary

Placements24 in South Africa seeks an Analytical Chemist to join its Pharmaceutical Development team in Tembisa. You will develop and validate analytical methods for raw materials and finished products, perform routine testing with HPLC, GC-MS, UV-Vis, and contribute to regulatory filings.

The ideal candidate holds a Master's or PhD in Analytical/Organic Chemistry with 3+ years in pharma analytics, knowledge of USP/EP, and a meticulous, data-driven approach.

Qualifications

• Master's or Ph.D. in Analytical Chemistry, Organic Chemistry, or a related field.
• Minimum of 3 years of experience in pharmaceutical analytical development or quality control.
• Proficiency with analytical instrumentation, particularly HPLC and GC-MS.
• Strong understanding of pharmacopeial methods (USP, EP) and regulatory guidelines (ICH).
• Excellent problem-solving abilities and meticulous data analysis and documentation.

Responsibilities

• Develop, validate, and implement analytical methods for raw materials, in-process samples, and finished drug products.
• Perform routine and non-routine testing using HPLC, GC-MS, UV-Vis, and titration.
• Characterize physical and chemical properties of drug substances and intermediates.
• Investigate out-of-specification results and deviations, identifying root causes and corrective actions.
• Contribute to analytical sections for regulatory filings (IND, NDA).
• Maintain laboratory equipment and ensure GLP and GMP compliance.

Skills

Analytical chemistry

Data analysis

Problem solving

Education

Master's degree in Analytical Chemistry

PhD in Analytical/Organic Chemistry

Tools

HPLC

GC-MS

UV-Vis

Job description

Our client is actively seeking a skilled Analytical Chemist to join their dedicated Pharmaceutical Development team based in Tembisa . This role is critical for ensuring the quality and efficacy of pharmaceutical products through rigorous analytical testing and method development. You will be responsible for employing advanced analytical techniques to characterize drug substances and products, troubleshoot formulation challenges, and support regulatory submissions. The ideal candidate will possess a strong foundation in analytical chemistry and a passion for contributing to the development of life-saving medications within a facility committed to innovation and scientific excellence, working a hybrid schedule that balances remote flexibility with essential on-site laboratory work.

Key Responsibilities

• Develop, validate, and implement analytical methods for raw materials, in-process samples, and finished drug products.
• Perform routine and non-routine testing using techniques such as HPLC, GC, MS, UV-Vis, and titration.
• Characterize the physical and chemical properties of drug substances and intermediates.
• Investigate out-of-specification (OOS) results and deviations, identifying root causes and implementing corrective actions.
• Contribute to the preparation of analytical sections for regulatory filings (e.g., IND, NDA).
• Maintain laboratory equipment and ensure compliance with Good Laboratory Practices (GLP) and Good Manufacturing Practices (GMP).

Requirements

• Master's or Ph.D. in Analytical Chemistry, Organic Chemistry, or a related field.
• Minimum of 3 years of experience in pharmaceutical analytical development or quality control.
• Proficiency with various analytical instrumentation, particularly HPLC and GC-MS .
• Strong understanding of pharmacopeial methods (USP, EP) and regulatory guidelines (ICH).
• Excellent problem-solving abilities and meticulous attention to detail in data analysis and documentation.

Benefits

• Competitive annual salary and potential for performance bonuses.
• Comprehensive medical aid and retirement fund benefits.
• Hybrid work model offering a balance between office and remote work.
• Opportunities for professional growth and continuous learning in pharmaceutical sciences.
• Access to modern laboratory equipment and a supportive team environment in Tembisa .