Senior Analytical Chemist - Pharmaceutical QC

Placements24; Pretoria; Hybrid; ZAR 900,000 - 1,300,000; Full time

Benefits offered by this job

Competitive salary

Hybrid work model

Professional growth

Health & retirement

Supportive environment

Job summary

Placements24 in Pretoria seeks a Senior Analytical Chemist to lead QC analytics, method development and validation in a hybrid lab setting.

You will mentor staff, review data for cGMP compliance, and support regulatory filings.

The ideal candidate holds an MSc or PhD in Chemistry or Pharmaceutical Sciences and 5+ years of pharma analytical experience with HPLC/GC and spectroscopy, plus strong problem-solving and teamwork.

Qualifications

• M.Sc. or Ph.D. in Chemistry, Pharmaceutical Sciences, or related field.
• Minimum of 5 years of experience in pharmaceutical analytical chemistry and QC environments.
• Expertise in chromatography (HPLC, GC) and spectroscopic techniques (UV-Vis, IR, MS).
• Thorough understanding of cGMP regulations and pharmaceutical quality systems.
• Experience with method development, validation, and technology transfer.
• Strong problem-solving skills and ability to work effectively in a team-oriented, hybrid setting.

Responsibilities

• Develop, validate, and transfer analytical methods (e.g., HPLC, GC, KF, UV-Vis) for raw materials, in-process samples, and finished products.
• Perform routine and non-routine analytical testing, troubleshooting, and investigations for out-of-specification results.
• Operate and maintain analytical instrumentation, ensuring calibration and suitability for use.
• Review and approve analytical data, ensuring compliance with cGMP, ICH, and other regulatory guidelines.
• Author method validation reports, technical reports, and contribute to regulatory filings.
• Train and mentor junior analytical chemists and laboratory technicians.

Skills

Analytical chemistry

Leadership experience

Troubleshooting

Team collaboration

Education

MSc./PhD in Chemistry or Pharmaceutical Sciences

Tools

HPLC

GC

KF

UV-Vis

IR

MS

Job description

About the Role

Our client is seeking a highly skilled Senior Analytical Chemist to enhance their Quality Control (QC) department in Pretoria . This role is crucial for ensuring the quality, safety, and efficacy of pharmaceutical products through rigorous analytical testing. You will be responsible for developing, validating, and implementing analytical methods, troubleshooting instrumentation, and ensuring compliance with regulatory standards. Working in a hybrid capacity, you will have the opportunity to contribute significantly to product integrity while maintaining a balance between on-site laboratory work and remote data analysis/reporting. This is an excellent opportunity for an experienced analytical chemist to take on a leadership role within a critical function.

Key Responsibilities

• Develop, validate, and transfer analytical methods (e.g., HPLC, GC, KF, UV-Vis) for raw materials, in-process samples, and finished products.
• Perform routine and non-routine analytical testing, troubleshooting, and investigations for out-of-specification results.
• Operate and maintain analytical instrumentation, ensuring calibration and suitability for use.
• Review and approve analytical data, ensuring compliance with cGMP, ICH, and other regulatory guidelines.
• Author method validation reports, technical reports, and contribute to regulatory filings.
• Train and mentor junior analytical chemists and laboratory technicians.

Requirements

• M.Sc. or Ph.D. in Chemistry, Pharmaceutical Sciences, or a related field.
• Minimum of 5 years of experience in pharmaceutical analytical chemistry and QC environments.
• Expertise in chromatography (HPLC, GC) and spectroscopic techniques (UV-Vis, IR, MS).
• Thorough understanding of cGMP regulations and pharmaceutical quality systems.
• Experience with method development, validation, and technology transfer.
• Strong problem-solving skills and ability to work effectively in a team-oriented, hybrid setting.

Benefits

• Competitive salary and benefits package.
• Hybrid work model offering flexibility.
• Opportunities for professional growth and continuous learning in Pretoria .
• Comprehensive health, retirement, and wellness programs.
• A supportive and quality-focused work environment.