Analytical Chemist - Pharmaceutical Development

Placements24; Kempton Park; Hybrid; ZAR 650,000 - 900,000; Full time

Benefits offered by this job

Hybrid work model

Medical aid

Retirement fund

Growth opportunities

Modern lab equipment

Job summary

Placements24 in Gauteng seeks an Analytical Chemist for its Pharmaceutical Development team in Tembisa. You will develop and validate analytical methods, perform routine and non-routine testing with HPLC, GC-MS, UV-Vis, and titration, and support regulatory submissions, under GLP/GMP guidelines in a hybrid lab setting.

The ideal candidate holds a Master’s or PhD in Analytical/Organic Chemistry, with 3+ years in pharma analytics, and a meticulous approach to data analysis, documentation, and

Qualifications

• Master's or Ph.D. in Analytical Chemistry, Organic Chemistry, or a related field.
• Minimum of 3 years of experience in pharmaceutical analytical development or quality control.
• Proficiency with various analytical instrumentation, particularly HPLC and GC-MS.
• Strong understanding of pharmacopeial methods (USP, EP) and regulatory guidelines (ICH).
• Excellent problem-solving abilities and meticulous attention to detail in data analysis and documentation.

Responsibilities

• Develop, validate, and implement analytical methods for raw materials, in-process samples, and finished drug products.
• Perform routine and non-routine testing using techniques such as HPLC, GC, MS, UV-Vis, and titration.
• Characterize the physical and chemical properties of drug substances and intermediates.
• Investigate out-of-specification (OOS) results and deviations, identifying root causes and implementing corrective actions.
• Contribute to the preparation of analytical sections for regulatory filings (e.g., IND, NDA).
• Maintain laboratory equipment and ensure compliance with Good Laboratory Practices (GLP) and Good Manufacturing Practices (GMP).

Skills

Analytical chemistry

Problem solving

Data analysis

Quality control

Education

Master's or PhD in Analytical/Organic Chemistry or related field

Tools

HPLC

GC-MS

UV-Vis

Titration

Job description

About the Role

Our client is actively seeking a skilled Analytical Chemist to join their dedicated Pharmaceutical Development team based in Tembisa. This role is critical for ensuring the quality and efficacy of pharmaceutical products through rigorous analytical testing and method development. You will be responsible for employing advanced analytical techniques to characterize drug substances and products, troubleshoot formulation challenges, and support regulatory submissions. The ideal candidate will possess a strong foundation in analytical chemistry and a passion for contributing to the development of life-saving medications within a facility committed to innovation and scientific excellence, working a hybrid schedule that balances remote flexibility with essential on-site laboratory work.

Key Responsibilities

• Develop, validate, and implement analytical methods for raw materials, in-process samples, and finished drug products.
• Perform routine and non-routine testing using techniques such as HPLC, GC, MS, UV-Vis, and titration.
• Characterize the physical and chemical properties of drug substances and intermediates.
• Investigate out-of-specification (OOS) results and deviations, identifying root causes and implementing corrective actions.
• Contribute to the preparation of analytical sections for regulatory filings (e.g., IND, NDA).
• Maintain laboratory equipment and ensure compliance with Good Laboratory Practices (GLP) and Good Manufacturing Practices (GMP).

Requirements

• Master's or Ph.D. in Analytical Chemistry, Organic Chemistry, or a related field.
• Minimum of 3 years of experience in pharmaceutical analytical development or quality control.
• Proficiency with various analytical instrumentation, particularly HPLC and GC-MS .
• Strong understanding of pharmacopeial methods (USP, EP) and regulatory guidelines (ICH).
• Excellent problem-solving abilities and meticulous attention to detail in data analysis and documentation.

Benefits

• Competitive annual salary and potential for performance bonuses.
• Comprehensive medical aid and retirement fund benefits.
• Hybrid work model offering a balance between office and remote work.
• Opportunities for professional growth and continuous learning in pharmaceutical sciences.
• Access to modern laboratory equipment and a supportive team environment in Tembisa .