Translational Imaging Lead (Senior Principal Scientist)

Novartis AG; Pennsylvania; On-site; USD 139,000 - 283,000; Full time

Job summary

Novartis seeks an experienced Senior Principal Scientist/Associate Director to lead the Translational Profiling group within Discovery Sciences in Cambridge, MA. The role combines scientific leadership with hands-on bench work to advance state-of-the-art imaging and spatial biology platforms for target discovery and mechanism studies.

You will mentor a matrix team of scientists, shape strategy for imaging capabilities, and collaborate across therapeutic areas and external partners to accelerate

Qualifications

• Ph.D. in Biology or related life sciences with 7+ years of postgraduate research experience in drug discovery.
• Hands-on expertise in confocal and advanced imaging techniques.
• Experience leading matrix teams and mentoring scientists.
• Interest in AI-enabled imaging, omics, and multidimensional data analysis.

Responsibilities

• Lead translational biology, imaging, and profiling strategies across drug discovery pipelines.
• Develop assays and workflows leveraging imaging, spatial biology, and proteomics.
• Maintain active bench presence and guide experimental design and data interpretation.
• Collaborate with project teams, platform scientists, and disease-area researchers to drive outcomes.

Skills

Biology research leadership

Advanced imaging

Team mentorship

Cross-functional collaboration

Education

PhD in Biology or related life sciences

Job description

Novartis seeks an experienced Senior Principal Scientist/Associate Director to lead the Translational Profiling group within Discovery Sciences in Cambridge, MA. The role combines scientific leadership with hands-on bench work to advance state-of-the-art imaging and spatial biology platforms for target discovery and mechanism studies.

You will mentor a matrix team of scientists, shape strategy for imaging capabilities, and collaborate across therapeutic areas and external partners to accelerate