Senior Biomarker Assay Development Leader

Novartis

Cambridge (MA)

On-site

USD 153,000 - 283,000

Full time

3 days ago

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Job summary

Novartis in Cambridge, MA seeks a Sr Principal Scientist / Associate Director, Biomarker Assay Development Laboratory to lead a high-performing team and develop innovative biomarker assays that shape decisions across discovery and clinical development.

You will design fit-for-purpose assay strategies, drive operations, mentor scientists, and collaborate with Translational Medicine, Data Science, and external partners to deliver high-quality translational data.

Qualifications

PhD or MD in life sciences or equivalent.
Extensive experience developing biomarker assays in pharma/biotech.
Strong leadership and collaboration across cross-functional teams.

Responsibilities

Lead development and qualification of biomarker assays supporting discovery, translational research, and clinical development.
Design fit-for-purpose assay strategies enabling target engagement, pharmacodynamics, and patient stratification decisions.
Drive laboratory operations, resource planning, and prioritization to support portfolio objectives.
Build, mentor, and develop a high-performing team of biomarker scientists.
Foster a culture of scientific excellence, accountability, collaboration, and continuous improvement.
Partner with Translational Medicine, Data Science, and cross-functional project teams on biomarker strategies.
Establish and manage external collaborations to access emerging technologies and capabilities.
Oversee outsourced assay activities and ensure delivery of high-quality translational data.
Provide scientific leadership that informs translational plans and clinical development strategies.
Represent the laboratory in cross-functional forums and contribute to strategic program decisions.