Director, Translational Neurodegeneration Medicine

Novartis Group Companies; Cambridge (MA); Híbrido; USD 249.000 - 462.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Comprehensive benefits

Descripción de la vacante

Novartis Group of Companies in Cambridge, MA, is seeking a Director, Translational Medicine Expert (Neurodegeneration) to lead end-to-end translational strategy bridging preclinical research to early clinical development. You will drive biomarker strategies, clinical endpoint selection, and phase 1/2 trial design to enable data-driven decisions.

The role requires cross-functional leadership across TM, Clinical Development, Biomarker Development, and Regulatory, with responsibility for external

Formación

• MD, neurologists, clinical training in neurodegenerative diseases.
• Experience in translational medicine, early clinical development, or experimental therapeutics.
• Ability to shape development strategies and support differentiation.

Responsabilidades

• Define and execute integrated translational strategies across neurodegeneration programs.
• Lead translational components from preclinical Phase 1/2 clinical studies.
• Drive program progression through key decision gates (e.g., IND, TDP, IDPA).
• Ensure mechanistic linkage between target biology, biomarkers, and endpoints.
• Obtain external collaborations and advance patient-centered development.

Conocimientos

Clinical Trials

Data Analysis

Data Monitoring

Drug Development

Medical Research

People Management

Educación

MD

PhD / PharmD

Clinical training in neurodegenerative diseases

Descripción del empleo

Novartis Group of Companies in Cambridge, MA, is seeking a Director, Translational Medicine Expert (Neurodegeneration) to lead end-to-end translational strategy bridging preclinical research to early clinical development. You will drive biomarker strategies, clinical endpoint selection, and phase 1/2 trial design to enable data-driven decisions.

The role requires cross-functional leadership across TM, Clinical Development, Biomarker Development, and Regulatory, with responsibility for external