Strategic Transformation Leader – Enterprise Programs

Mckesson Corporation; Irving (TX); On-site; USD 170,000 - 284,000; Full time

Job summary

McKesson, a Fortune 10 healthcare leader, seeks a Principal Program Manager to shape and operationalize Enterprise Applications strategy. You will translate priorities into actionable roadmaps, partner with senior executives, and drive measurable business impact across complex, matrixed environments.

You will lead multi‑year plans, establish governance, manage investments, and influence senior leaders to realize strategic value and ROI.

Qualifications

• Bachelor’s degree in Business, Strategy, Engineering, Finance, or a related field (MBA or equivalent preferred).
• 10+ years of experience in strategy, management consulting, transformation, program leadership, or equivalent roles.
• Proven experience leading complex, cross‑functional initiatives with executive visibility.
• Strong strategic planning, analytical, problem‑solving, and financial management skills, including ROI.
• Demonstrated ability to influence without authority in a matrixed organization.
• Experience managing strategic vendors and partner relationships, including contract governance, performance management, negotiations, and service delivery oversight.

Responsibilities

• Lead development of multi-year strategic plans aligned to enterprise priorities and financial targets.
• Translate strategy into goals, success metrics, and execution roadmaps across portfolios and teams.
• Assess trends, risks, and opportunities to inform strategic decision‑making.
• Develop business cases, investment strategies, and financial models to evaluate opportunities and optimize resource allocation.
• Drive execution of strategic initiatives with cross‑functional alignment across business, technology, finance, and operations.
• Establish governance, prioritization, and performance tracking for strategic programs and investments.

Skills

Strategic planning

Financial management

Executive stakeholder management

Cross-functional leadership

Vendor management

Education

Bachelor’s degree in Business/Strategy/Engineering/Finance

MBA or equivalent preferred

Job description

McKesson, a Fortune 10 healthcare leader, seeks a Principal Program Manager to shape and operationalize Enterprise Applications strategy. You will translate priorities into actionable roadmaps, partner with senior executives, and drive measurable business impact across complex, matrixed environments.

You will lead multi‑year plans, establish governance, manage investments, and influence senior leaders to realize strategic value and ROI.