Senior Program Manager, Enterprise Integration & Modernization

McKesson Corporation

Irving (TX)

On-site

USD 170,000 - 284,000

Full time

14 days+

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Equal Employment Opportunity Employer

Job summary

McKesson Corporation is seeking a strategic Principal Program Manager for Enterprise Integration to lead large-scale modernization programs across our technology ecosystem. You will drive cross-functional initiatives including cloud migration, middleware modernization, and integration platforms to enable business growth and regulatory compliance.

Responsibilities include portfolio governance, financial stewardship, roadmaps, and executive alignment across multiple units.

Qualifications

13+ years of IT program management or enterprise transformation experience.
Bachelor's degree in Information Technology, Computer Science, Engineering, Information Systems, Business, or a related field.
Experience with MuleSoft, IBM MQ, IBM MFT, SAP BODS, Azure, GCP, API integration platforms, or enterprise middleware technologies.
Experience leading large-scale, enterprise-wide technology transformation programs with executive-level visibility.
Experience managing complex cross-functional portfolios with multiple stakeholders.
Experience with budgets, forecasts, and portfolio investment decisions.
Experience with enterprise integration technologies, middleware, APIs, cloud migration, or modernization programs.
Experience managing external partners or vendors.
Strong executive communication, governance, and risk management capabilities.
Experience with ITGC, SOX, HIPAA, DSCSA or similar regulatory frameworks.
Experience developing business cases, ROI analyses, and TCO-based investment recommendations.
Strong vendor relationship management skills.

Responsibilities

Lead enterprise-wide integration and modernization programs from strategy through execution, ensuring on-time, on-budget delivery.
Drive transformation initiatives including MuleSoft platform evolution, middleware modernization, cloud migration, IBM MFT/MQ modernization, SAP BODS upgrades, and IaaS strategies.
Develop and manage multi-year program roadmaps, dependencies, risks, and delivery metrics across organizations.
Establish portfolio governance and executive reporting frameworks for visibility into health, outcomes, value, and priorities.
Lead strategic vendor and managed services relationships with performance management and KPI tracking.
Drive platform rationalization and Total Cost of Ownership optimization through lifecycle planning and licensing strategies.
Collaborate with EARB, security, compliance, and audit teams to ensure regulatory adherence.
Align senior stakeholders across multiple business units to achieve strategic objectives.