Strategic Commercial Operations Leader — Remote

Openkrill; United States; Hybrid; USD 180,000 - 240,000; Full time

Benefits offered by this job

Hybrid work model

Job summary

Karius seeks a Director of Commercial Operations to lead sales systems, processes, and analytics, partnering with Sales, Marketing, and Finance to drive revenue growth. This role reports to the Chief Commercial Officer and supports multi-year growth with data-driven decisions.

The position focuses on forecasting accuracy, territory design, incentives, and cross-functional collaboration across a growing life sciences business.

Qualifications

• Bachelor's degree required; MBA preferred.
• 10+ years of commercial/sales operations experience with a degree; 4+ years in people management.
• Experience architecting and scaling CRM, sales automation, and analytics.

Responsibilities

• Own the strategy and architecture for sales operations, including CRM systems, sales automation, territory design, and analytics.
• Build and lead a high-performing commercial operations team.
• Establish and govern sales goals, metrics, and KPIs.
• Own end-to-end sales forecasting, pipeline analysis, forecast prep, scenario modeling and reporting.
• Design and govern sales compensation structures and incentives with Finance and HR.
• Oversee vendor strategy and budget for the commercial tech stack.
• Lead change management for new tools and processes.
• Identify cross-sell and upsell opportunities with Sales leadership.
• Ensure data integrity across CRM and other systems.

Skills

Sales forecasting

CRM systems

Leadership

Education

Bachelor's degree in Business, Marketing, Operations, or related field

MBA preferred

Tools

Salesforce

Job description

Karius seeks a Director of Commercial Operations to lead sales systems, processes, and analytics, partnering with Sales, Marketing, and Finance to drive revenue growth. This role reports to the Chief Commercial Officer and supports multi-year growth with data-driven decisions.

The position focuses on forecasting accuracy, territory design, incentives, and cross-functional collaboration across a growing life sciences business.