Sr. Director, Launch Excellence & Operations

Immatics US; United States; Remote; USD 250,000 - 290,000; Full time

Job summary

Immatics US is seeking a Senior Director, Launch Excellence & Operations to partner with the VP to shape the commercial launch strategy and governance for high-impact cancer therapies. The role sits at the center of planning, execution, and cross-functional alignment, ensuring readiness for field deployment.

You will drive integrated planning, manage LRR processes, and establish operating rhythms and performance metrics to enable a successful, patient-focused commercial launch in the US.

Qualifications

• Requires 15+ years of relevant experience or 12+ years with MBA/advanced degree.
• Experience in biopharma commercial strategy, operations, or launch leadership.
• Proven ability to drive decisions across functions without direct authority.

Responsibilities

• Develop and execute integrated launch strategy, roadmap, and playbook.
• Govern Launch Readiness Review (LRR) and cross-functional governance.
• Lead operational readiness and performance monitoring for cell-therapy launches.

Skills

Strategy experience

Cross-functional leadership

Analytics & governance

Commercial launch planning

Education

Bachelor's degree in life sciences/business/engineering

MBA or equivalent advanced degree

Tools

Strategy consulting

Job description

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME , a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Why Join Us?

• Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
• Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
• Global Impact: Contribute to therapies that make a lasting impact on patients globally.

Role Overview

The Senior Director, Launch Excellence & Operations serves as a strategic partner and deputy to the VP, Launch Excellence, Strategy & Operations, helping shape and execute Immatics' commercial launch strategy. This highly visible role sits at the center of launch planning, governance, and operational readiness, ensuring cross-functional alignment and execution as the organization prepares for commercialization.

The successful candidate will lead integrated launch planning, support the Launch Readiness Review (LRR) process, and establish the operating rhythms, governance, and performance management frameworks necessary to drive launch success. This individual will operate seamlessly between strategy and execution, translating insights into action, guiding critical business decisions, and creating clarity in a dynamic and evolving environment.

Reports to: Vice President, Launch Excellence, Strategy & Operations

Location: US, Fully Remote

Salary Range: $250,000 - $290,000

Basic Qualifications:

• Bachelor's degree in life sciences, business, engineering, or a related field with 15+ years of relevant experience OR
• MBA / advanced degree (MBA, PhD, MD, or equivalent) with 12+ years of relevant experience A combination of top-tier strategy consulting experience and in-house biopharmaceutical commercial strategy, commercial operations, or launch leadership experience.

Preferred Qualifications:

• 5+ years in oncology; direct experience with TCR, CAR-T, or TIL cell therapies, including a first wave of commercial launch strongly preferred
• Demonstrated ownership of commercial launch strategy or launch readiness - including launch planning, cross-functional governance, milestone and risk management, and readiness tracking through to launch.
• Knowledge of personalized manufacturing and vein-to-vein logistics, including manufacturing slot allocation and patient journey management.
• Understanding of the melanoma treatment landscape, therapeutic decision-making, and patient access barriers.
• Working knowledge of the cell therapy operational value chain - treatment center authorization, apheresis scheduling, chain of identity / chain of custody, and product delivery.
• Experience standing up launch governance, a launch readiness review process, or a commercial PMO from scratch.
• Familiarity with digital launch excellence tools and analytics.
• Experience scoping and managing external consultants, agencies, and analytics vendors.
• Proven ability to drive strategic decision-making across functions without direct authority: framing the decision, assembling the analysis, aligning stakeholders, and driving the issue to closure.
• Exceptional executive communication, influencing, and synthesis skills; able to distill complex, ambiguous cross-functional situations into a clear recommendation
• Strong strategic planning and operational execution skills.

In this role you will:

• Launch Strategy & Commercial Planning
  Partner with the VP to develop and execute an integrated launch strategy, roadmap, and commercial playbook.
  Lead strategic evaluation and business cases for critical commercial decisions, capabilities, and growth opportunities.
  Continuously refine launch strategy based on market, competitive, regulatory, and operational insights.
  Develop executive recommendations and materials for senior leadership and key governance forums.
• Launch Governance & Cross-Functional Integration
  Drive cross-functional alignment, decision-making, and accountability through the Launch Readiness Review (LRR) process.
  Co-own launch readiness planning, including critical milestones, dependencies, risks, and mitigation strategies.
  Establish and maintain operating rhythms, governance processes, and communication forums that support launch execution.
  Facilitate resolution of complex cross-functional issues and ensure timely escalation of key decisions.
• Operational Readiness & Cell Therapy Operations Performance
  Build and monitor performance frameworks across the end-to-end cell therapy patient journey.
  Partner with operational teams to identify and address patient funnel attrition, process bottlenecks, and execution risks.
  Provide commercial leadership for systems, analytics, and reporting capabilities that enable launch readiness