Senior Software Engineer - LIMS & AWS Cloud Platforms

Personalis; Fremont (CA); On-site; USD 150,000 - 175,000; Full time

Benefits offered by this job

Medical, dental, vision

401(k) match

ESPP

Tuition reimbursement

Sick/vacation time

Commuter benefits / EV charging

Onsite gym

Wellness benefits

Job summary

Personalis, Inc. is seeking a Sr. Software Engineer to design, develop, and maintain our Laboratory Information Management Systems (LIMS).

You will own feature development for existing systems and new cloud platforms, partnering with senior engineers to deliver scalable, regulated solutions that power our laboratory operations. The role focuses on backend services in AWS, relational and graph databases, and REST APIs, with on-site work required M/T/W/Th.

Qualifications

• B.S. degree in Computer Science, Engineering, or a related technical field.
• 5 years of professional software development experience.
• Strong proficiency in at least one programming language such as Python or Java.
• Proven experience building and deploying applications on AWS.
• Solid experience with relational databases (e.g., PostgreSQL, MySQL) and developing REST APIs.
• Experience with version control systems (e.g., Github, Bitbucket) and CI/CD concepts.
• Excellent problem-solving skills and the ability to work independently on complex tasks.

Responsibilities

• Design, develop, test, and maintain software systems and features supporting laboratory operations.
• Develop and optimize backend services and APIs using Python and/or Java.
• Implement solutions using a variety of database technologies, including relational and graph databases.
• Take ownership of deploying and maintaining services in our AWS cloud environment.
• Actively participate in code reviews, design discussions, and technical documentation to ensure quality and maintainability.
• Troubleshoot and resolve complex technical issues in development and production environments.
• Collaborate with cross-functional teams to translate business requirements into robust technical solutions.

Skills

Python

Java

AWS

REST APIs

CI/CD

Git

Education

B.S. in Computer Science or related field

Tools

PostgreSQL

MySQL

Flask/FastAPI

Docker

Graph databases

GitHub

Job description

Personalis, Inc. is seeking a Sr. Software Engineer to design, develop, and maintain our Laboratory Information Management Systems (LIMS).

You will own feature development for existing systems and new cloud platforms, partnering with senior engineers to deliver scalable, regulated solutions that power our laboratory operations. The role focuses on backend services in AWS, relational and graph databases, and REST APIs, with on-site work required M/T/W/Th.