Senior Scientist, Protein Engineering & Genome Editing

Arbor Biotechnologies; Cambridge (MA); On-site; USD 120,000 - 150,000; Full time

Job summary

Arbor Biotechnologies in Cambridge, MA seeks a Scientist / Senior Scientist, Protein Engineering to drive experimental execution for protein engineering workstreams within genome editing programs. You will apply biochemistry, molecular biology, structure-function analysis, and cellular screening to generate improved genome editing molecules.

You will design and execute experiments, evaluate mutants, analyze data, and translate results into clear recommendations shaping next-step decisions.

Qualifications

• PhD with 2+ years post‑PhD industry/postdoc in protein engineering.
• Experience with CRISPR genome editing and enzymology.
• Ability to design and troubleshoot complex experiments.
• Strong data analysis and cross‑functional collaboration.

Responsibilities

• Design, execute, and evaluate protein engineering experiments aligned with campaign goals.
• Develop protein mutants/variants to support genome editing programs.
• Analyze biochemical and cellular data to guide next steps.
• Collaborate with computational scientists and project leads.
• Prepare and present results to project teams.

Skills

Protein engineering

CRISPR gene editing

Molecular biology

Data analysis

Experimentation

Education

PhD in biology/biochemistry or related

Tools

PyMOL

ChimeraX

AlphaFold

Illumina sequencing

Job description

Arbor Biotechnologies in Cambridge, MA seeks a Scientist / Senior Scientist, Protein Engineering to drive experimental execution for protein engineering workstreams within genome editing programs. You will apply biochemistry, molecular biology, structure-function analysis, and cellular screening to generate improved genome editing molecules.

You will design and execute experiments, evaluate mutants, analyze data, and translate results into clear recommendations shaping next-step decisions.