In Vivo Pharmacology Associate - Gene Editing Programs

Arbor; Cambridge (MA); In loco; USD 85.000 - 95.000; Tempo pieno

Vantaggi offerti da questo lavoro

Bonus eligibility

Equity

Parental leave 12 weeks

Parking or transit

401(k) match

HSA deductible coverage

Descrizione del lavoro

Arbor Biotechnologies in Cambridge, MA, seeks an experienced scientist to drive in vivo pharmacology studies in rodents, from dosing through tissue collection to molecular readout, supporting preclinical and IND-enabling work.

The role reports to the Senior Scientist, In Vivo Pharmacology, is on-site in Cambridge (4–5 days/week), and will set up studies, coordinate between lab and animal facility, process tissues, run assays (qPCR, ddPCR, RT-qPCR, Western blot, ELISA, RNAscope), and present

Competenze

• Bachelor's degree in pharmacology, biology, neuroscience, molecular biology or related field with 3+ years of industry experience or a Master's with 1+ year.
• Hands-on in vivo rodent studies including dosing, monitoring, blood collection, tissue harvest and necropsy.
• Able to dose rodents by IV, retro-orbital or similar routes.
• Able to process animal tissues and samples for molecular/biochemical endpoints.
• Experience with molecular/biochemical assays (qPCR/ddPCR, RT-qPCR, Western blot, ELISA, RNAscope); flow cytometry preferred.
• Has managed projects or studies and supported IND-enabling work.

Mansioni

• Run in vivo pharmacology studies in rodents, including dosing, monitoring, blood collection, tissue harvest and necropsy.
• Set up and schedule studies; coordinate between lab and animal facility.
• Process tissues and samples; isolate DNA, RNA, and protein for analyses.
• Run assays such as qPCR, ddPCR, RT-qPCR, Western blot, ELISA or RNAscope.
• Analyze, interpret, and graph study and assay data; present to project teams.
• Maintain study records, sample inventories, and protocols current and accurate.

Conoscenze

In vivo pharmacology

Rodent dosing

Study design coordination

Formazione

Bachelor's degree in pharmacology/biology/neuroscience/molecular biology or related field

Master's degree (1+ year experience)

Strumenti

qPCR

ddPCR

RT-qPCR

Western blot

ELISA

RNAscope

Flow cytometry

Descrizione del lavoro

Arbor Biotechnologies in Cambridge, MA, seeks an experienced scientist to drive in vivo pharmacology studies in rodents, from dosing through tissue collection to molecular readout, supporting preclinical and IND-enabling work.

The role reports to the Senior Scientist, In Vivo Pharmacology, is on-site in Cambridge (4–5 days/week), and will set up studies, coordinate between lab and animal facility, process tissues, run assays (qPCR, ddPCR, RT-qPCR, Western blot, ELISA, RNAscope), and present