Senior Scientist, Pharmacokinetics & PK/PD Leader

MSD Malaysia; Boston (MA); On-site; USD 176,000 - 277,000; Full time

Benefits offered by this job

Medical

Dental

Vision

401(k)

Holidays

Vacation

Sick days

Job summary

MSD Malaysia in Boston seeks a Principal Scientist to lead drug metabolism and PK/PD efforts across modalities. You will drive discovery testing funnels, generate and interpret PK/PD datasets, and communicate findings to multi-disciplinary teams, contributing to immunology and oncology portfolios.

The role requires a Ph.D. (or equivalent Master’s with extensive experience) and a proven track record in translational pharmacology, with leadership and collaboration across global discovery units.

Qualifications

• Ph.D. with 6+ years of relevant experience or Master’s with 10+ years in biochemistry, pharmacology or related fields.
• Experience leading DMPK discoveries for small molecules, peptides or proteins.
• Ability to analyze ADME/PK/PD data and interpret translational relevance.

Responsibilities

• Lead DMPK activities across multiple modalities within oncology and immunology.
• Characterize in vitro and in vivo ADME and PK properties of candidates.
• Design and analyze studies to relate drug disposition to PK/PD and safety.
• Manage PDMB scientists and develop bioanalytical strategies.
• Collaborate across Boston, South San Francisco and West Point teams.

Skills

DMPK Leadership

ADME

PKPD Modeling

Cross-Functional Teamwork

LAb Leadership

Education

Ph.D. (6+ years)

Master’s (10+ years)

Tools

Phoenix WinNonlin

Berkeley Madonna

MATLAB

Job description

MSD Malaysia in Boston seeks a Principal Scientist to lead drug metabolism and PK/PD efforts across modalities. You will drive discovery testing funnels, generate and interpret PK/PD datasets, and communicate findings to multi-disciplinary teams, contributing to immunology and oncology portfolios.

The role requires a Ph.D. (or equivalent Master’s with extensive experience) and a proven track record in translational pharmacology, with leadership and collaboration across global discovery units.