Senior Scientist - Neuroimmunology & iPSC Modeling

MSD

Boston (MA)

On-site

USD 119,000 - 188,000

Full time

3 days ago
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Job summary

MSD in Boston seeks an independent and motivated Senior Scientist with a background in cell biology, immunology, or neuroscience to validate and advance neuroimmune targets for CNS diseases. You will design and execute in vitro experiments, establish iPSC-based model systems, and lead translational research efforts.

The candidate will work 90% in the lab, collaborate across disciplines, and contribute to publications and internal program decisions within a dynamic, mission-driven team.

Qualifications

  • PhD in molecular/cell biology or neuroscience with post‑doc or industry experience.
  • Strong independent and collaborative work style.
  • Experience with CNS iPSC culture and complex in vitro models.

Responsibilities

  • Develop and troubleshoot new cell-based assays and analyses.
  • Lead complex experimental programs and interpret multidimensional data.
  • Isolate/characterize tissues, blood, PBMCs and iPSC-derived cells using immunocytochemistry, DNA/RNA isolation, PCR and RNA-seq.
  • Provide scientific oversight of external collaborations and study designs.
  • Communicate data clearly to teams and stakeholders.
  • Stay updated with literature and emerging tech to shape research direction.
  • Contribute to model system development and publications.

Skills

Independent thinker
CNS iPSC culture
Immunocytochemistry
DNA/RNA prep
qPCR
Western blot
ELISA
Data analysis
AI data QA
Scientific leadership
Scientific communication

Education

PhD in Molecular Cell Biology/Neuroscience/Pharmacology/Biology

Tools

NanoString
PCR
RNA-seq
Immunocytochemistry
qPCR
Western blot
Lentiviral vectors

Job description

MSD in Boston seeks an independent and motivated Senior Scientist with a background in cell biology, immunology, or neuroscience to validate and advance neuroimmune targets for CNS diseases. You will design and execute in vitro experiments, establish iPSC-based model systems, and lead translational research efforts.

The candidate will work 90% in the lab, collaborate across disciplines, and contribute to publications and internal program decisions within a dynamic, mission-driven team.

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