Senior Pharmacology Scientist (In Vivo & Immunology)

BIOCYTOGEN LLC; Waltham (MA); Vor Ort; USD 120.000 - 190.000; Vollzeit

Benefits dieser Stelle

Medical Insurance

Dental Insurance

Vision Insurance

Health Reimbursement Accounts

Life and AD&D Insurance

Short & Long Term Disability Insurance

401K with Company Match

Paid Time Off

Paid Sick Days & Holidays

Zusammenfassung

Biocytogen Boston Corp is seeking a highly motivated Pharmacology Scientist to support both in vivo and in vitro preclinical research across immunology, immuno-oncology, metabolic disease and neurology. The role combines hands-on experiments with project management to service biotech and pharma clients.

The successful candidate will lead animal studies, develop humanized models, perform flow cytometry, ELISA and QRT-PCR, and mentor junior staff while collaborating with cross-functional teams and

Qualifikationen

• PhD in pharmacology, immunology, cancer biology, or related biomedical field.
• Extensive hands-on experience in animal models and preclinical in vivo pharmacology.
• Proven skills in cell-based immunological assays including T cell activation, NK cell–mediated cytotoxicity, and macrophage functional assays.
• Proficiency in PK/PD model establishment and analysis.
• Expertise in flow cytometry, cytokine profiling (ELISA, qRT-PCR, multiplex assays), and immune cell isolation from tissues.
• Experience with surgical procedures in rodents is highly desirable.

Aufgaben

• Design and develop animal models; execute in vivo experiments to evaluate efficacy of novel agents.
• Lead in vivo service projects and preclinical studies, acting as Project Manager or Study Director.
• Perform animal handling, tumor inoculation, drug administration, blood/tissue collection, tumor measurements, and PK/PD studies.
• Design and execute internal model-building projects and characterize humanized mouse models.
• Provide troubleshooting and guidance to junior associates.
• Collaborate with BD/Sales for client planning and technical discussions; present results to clients and internal stakeholders.

Kenntnisse

In vivo pharmacology

In vitro assays

Flow cytometry

PK/PD modeling

Immune profiling

Tumor models

Ausbildung

PhD in pharmacology/ immunology/ cancer biology

Tools

qRT-PCR

ELISA

Western blot

Jobbeschreibung

Biocytogen Boston Corp is seeking a highly motivated Pharmacology Scientist to support both in vivo and in vitro preclinical research across immunology, immuno-oncology, metabolic disease and neurology. The role combines hands-on experiments with project management to service biotech and pharma clients.

The successful candidate will lead animal studies, develop humanized models, perform flow cytometry, ELISA and QRT-PCR, and mentor junior staff while collaborating with cross-functional teams and