In Vitro Neuroscience Scientist – Target Discovery

Bristol Myers Squibb; Cambridge (MA); On-site; USD 105,000 - 127,000; Full time

Benefits offered by this job

Stock opportunities

Flexible Time Off (FTO)

11 company holidays

Job summary

Bristol Myers Squibb in Cambridge, MA, seeks a Senior Associate Scientist – In vitro Biology, Neuroscience Discovery to investigate targets in neurodegenerative disease using human iPSC-based models.

You will design hypothesis-driven studies, develop assays, and collaborate across teams to advance drug discovery. A strong background in molecular/cellular biology and target validation is required, with experience in iPSC-derived neural models preferred.

Qualifications

• Experience developing and applying cellular assays for target validation and pharmacological characterization.
• Strong background in molecular and cellular biology with disease mechanism focus.
• Ability to translate biological questions into therapeutic hypotheses and present findings.

Responsibilities

• Design and execute hypothesis-driven studies to investigate novel therapeutic targets in neurodegenerative disease.
• Develop and apply advanced human iPSC-based models and disease-relevant assays to evaluate target biology.
• Design, optimize, and implement mechanistic and translational assays for target interrogation and drug-discovery progression.
• Establish causal relationships between target modulation and disease mechanisms using genetic and pharmacological approaches.
• Support SAR efforts by generating in vitro pharmacology data to inform compound optimization and progression.
• Represent Discovery Biology on cross-functional program teams, presenting results and interpretation.

Skills

Neuroscience

Molecular biology

Cell biology

iPSC models

Target validation

In vitro assays

Pharmacology

Data interpretation

Cross-functional collaboration

Education

Bachelor’s degree with 4+ years of academic and/or industry experience

Master’s degree with 2+ years of academic and/or industry experience

Tools

Human iPSC-based models

Job description

Bristol Myers Squibb in Cambridge, MA, seeks a Senior Associate Scientist – In vitro Biology, Neuroscience Discovery to investigate targets in neurodegenerative disease using human iPSC-based models.

You will design hypothesis-driven studies, develop assays, and collaborate across teams to advance drug discovery. A strong background in molecular/cellular biology and target validation is required, with experience in iPSC-derived neural models preferred.