Senior Scientist, LC-MS Analytics for Biologics

Randstad USA; St. Louis (MO); Presencial; USD 55.000 - 65.000; Jornada completa

Descripción de la vacante

Randstad USA is seeking a Senior Scientist for the Analytical R&D department at their St. Louis facility.

The role focuses on designing, validating, and implementing advanced LC‑MS assays to quantify proteins within complex biological mixtures, spanning from early development to manufacturing. Ideal candidates hold a BS in Chemistry and show hands‑on mastery of high‑resolution and triple quadrupole LC‑MS platforms, plus strong sample prep skills for large biomolecules and a collaborative,

Formación

• Bachelor of Science in Chemistry or related science field.
• Hands-on proficiency with high‑resolution and triple quadrupole LC‑MS platforms.
• Experience in sample preparation for large biomolecules (digestion, enrichment, depletion, labeling).
• Strong collaborative and independent problem‑solving with good scientific communication.

Responsabilidades

• Lead design, development, and validation of LC‑MS assays for quantifying proteins in complex mixtures.
• Characterize large biomolecules including monoclonal antibodies, multispecifics, and ADCs.
• Prepare complex samples using digestion, enrichment, depletion, and labeling techniques.
• Collaborate with product development, manufacturing, and project leaders to advance programs.
• Maintain, calibrate, and troubleshoot LC‑MS instrumentation.

Conocimientos

LC-MS systems

Triple quadrupole MS

Sample preparation

Collaboration

Educación

Bachelor of Science in Chemistry

Herramientas

High-resolution LC-MS

Triple quadrupole LC-MS

Descripción del empleo

Randstad USA is seeking a Senior Scientist for the Analytical R&D department at their St. Louis facility.

The role focuses on designing, validating, and implementing advanced LC‑MS assays to quantify proteins within complex biological mixtures, spanning from early development to manufacturing. Ideal candidates hold a BS in Chemistry and show hands‑on mastery of high‑resolution and triple quadrupole LC‑MS platforms, plus strong sample prep skills for large biomolecules and a collaborative,