Senior Scientist, Immuno-Oncology

SystImmune, Inc.; Washington (District of Columbia); On-site; USD 90,000 - 140,000; Full time

Benefits offered by this job

Health benefits

401(k) plan

PTO

Paid holidays

Job summary

SystImmune, Inc. in the United States is seeking a Senior Scientist to drive discovery and development of protein therapeutics and bispecific antibodies in an immuno-oncology program.

The role emphasizes hands-on work with leading biologics platforms and collaboration across disciplines. The ideal candidate has a PhD with 2–5+ years of relevant experience, strong immunology and tumor biology expertise, and a proactive, collaborative attitude to advance preclinical projects.

Qualifications

• PhD in immunology or cancer biology or related field.
• Background in human immune cell biology or immune cell signaling.
• Experience in discovery and development of protein therapeutics.
• Experience with bispecific antibodies preferred.
• Excellent time management and communication skills.

Responsibilities

• Establish in vitro and in situ models to identify and characterize novel antibody therapeutics.
• Evaluate pathways and mechanisms for immunological interventions and bispecific/combination strategies.
• Collaborate with interdisciplinary teams.
• Prepare reports and oral presentations on research projects.
• Prepare regulatory submission documents as needed.
• Lead immuno-oncology discovery/preclinical projects.

Skills

PhD in immunology

Tumor biology

Protein therapeutics

Bispecific antibodies

Mammalian cell culture

Strong communication

Education

PhD in immunology, cancer biology or related field

Tools

Incucyte

Emulate

MSD

FACS

Job description

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Bothell, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.

Senior Scientist

role isin theresearch anddevelopmentdivision. Theidealcandidateis a highly energeticandmotivated scientist with experience indiscoveryand development of protein therapeutics.Theposition requiresa strong backgroundinhumanimmunology,andtumor biology,as well ashands-on experience withmajorbiotechnologyplatformsfor biologics drug developmentIncucyte,Emulate, MSD, FACS, etc.

Responsibilities

• Establish and applyin vitro, andin situmodels toidentifyandcharacterize novelantibodytherapeutics
• Evaluate novel pathways and mechanisms for immunological therapeutic intervention and formulate strategies for bispecific andtherapeuticcombination approaches
• Work as part of highly collaborative interdisciplinary team
• Prepare written reportsto specificationand oral presentations on research projects
• Prepare documents for submission to domestic and international regulatory agencies
• Lead immuno-oncologydiscovery/preclinical projects
• Other duties as assigned

Qualifications

• PhDinimmunology,cancerbiologyor related field with2 - 5+ yearsof relevant academic and/or pharmaceutical or biotech experience
• Background inhumanimmunecell biology, orimmunecellreceptorsignalingresearch
• Expertisein discovery and development ofproteintherapeuticsand mammalian cell culture
• Research experienceindevelopingbispecific antibodiesispreferred
• Excellent time management and organizational skills
• Excellent written,oral,and interpersonal communication skills
• Possess the right attitude (agile, curious, positive, open-minded, “can-do” mindset), and have the ability andstrong desireto “make things happen”

Work Environment

Bench top work in a BSL-2 laboratory environment, including potential exposure to biohazards

Adherence to Health and Safety standards when working withtemperature-controlledsystems, including liquid and vapor phase liquid nitrogen

Physical DemandsOccasional lifting to 30 pounds

Requires repetitive multi-channel pipetting, single channel pipetting, and computer data entry

Fine motor movements in fingers/hands tooperatecomputers and other office and lab equipment, repetitive motion with lab equipment

Stooping, bending, crouching, reaching, or climbing ladders

Position Type/Expected Hours of Work

May need to work outside of standard working hours at times

This role is currently working onsite and is expected to work onsite for working hours, with flexibility to work start time. The work location for this role is in Redmond,WA

Travel

Attendance and participation in national and international conferences encouraged

Compensation and Benefits

The expected base salary range for this position is $90,000 - $140,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s level qualifications, experience, and skills.While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.

• SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.

We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.

SystImmune is an Equal Opportunity Employer. We welcome diverse talent.