Senior Scientist, Immuno-Oncology

SystImmune, Inc.; Redmond (WA); On-site; USD 90,000 - 140,000; Full time

Benefits offered by this job

Premium medical/dental/vision coverage

401(k) plan with company match

PTO 15 days

11 paid holidays

Job summary

SystImmune, Inc. in Redmond, WA is seeking a Senior Scientist to advance discovery and development of protein therapeutics in human immunology and tumor biology. The role is onsite with relocation of facilities to Bothell planned for fall 2026.

You will lead immuno-oncology projects, drive bispecific antibody programs, and collaborate across disciplines to deliver translational research and preclinical advances.

Qualifications

• PhD in immunology, cancer biology or related field with 2-5+ years of relevant academic and/or pharma/biotech experience.
• Background in human immune cell biology or immune cell receptor signaling research.
• Experience in discovery and development of protein therapeutics and mammalian cell culture.

Responsibilities

• Establish and apply in vitro and in situ models to identify and characterize novel antibody therapeutics.
• Lead immuno-oncology discovery/preclinical projects and collaborate with cross-functional teams.
• Prepare written reports and oral presentations; submit documents to regulatory agencies.

Skills

Protein therapeutics development

Mammalian cell culture

Bispecific antibodies

Human immunology

Team collaboration

Communication

Education

PhD in immunology

Tools

IncuCyte

Emulate

MSD

Job description

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.

This Senior Scientist role isin theresearch anddevelopmentdivision. Theidealcandidateis a highly energeticandmotivated scientist with experience indiscoveryand development of protein therapeutics.Theposition requiresa strong backgroundinhumanimmunology,andtumor biology,as well ashands-on experience withmajorbiotechnologyplatformsfor biologics drug developmentIncucyte,Emulate, MSD, FACS, etc. Candidates with a passion for agentic AI-based system development are highly encouraged to apply.

This role is full-time onsite at our Redmond, WA location and we will be moving to our new building in Bothell, WA fall 2026.

Responsibilities

• Establish and applyin vitro, andin situmodels toidentifyandcharacterize novelantibodytherapeutics
• Evaluate novel pathways and mechanisms for immunological therapeutic intervention and formulate strategies for bispecific andtherapeuticcombination approaches
• Work as part of highly collaborative interdisciplinary team
• Prepare written reportsto specificationand oral presentations on research projects
• Prepare documents for submission to domestic and international regulatory agencies
• Lead immuno-oncologydiscovery/preclinical projects
• Other duties as assigned

Qualifications

• PhDinimmunology,cancerbiologyor related field with2 - 5+ yearsof relevant academic and/or pharmaceutical or biotech experience
• Background inhumanimmunecell biology, orimmunecellreceptorsignalingresearch
• Expertisein discovery and development ofproteintherapeuticsand mammalian cell culture
• Research experienceindevelopingbispecific antibodiesispreferred
• Excellent time management and organizational skills
• Excellent written,oral,and interpersonal communication skills
• Possess the right attitude (agile, curious, positive, open-minded, "can-do" mindset), and have the ability andstrong desireto "make things happen"

Work Environment

• Bench top work in a BSL-2 laboratory environment, including potential exposure to biohazards
• Adherence to Health and Safety standards when working withtemperature-controlledsystems, including liquid and vapor phase liquid nitrogen

Physical Demands

• Occasional lifting to 30 pounds
• Requires repetitive multi-channel pipetting, single channel pipetting, and computer data entry
• Fine motor movements in fingers/hands tooperatecomputers and other office and lab equipment, repetitive motion with lab equipment
• Stooping, bending, crouching, reaching, or climbing ladders

Position Type/Expected Hours of Work

• May need to work outside of standard working hours at times
• This role is currently working onsite and is expected to work onsite for working hours, with flexibility to work start time. The work location for this role is in Redmond,WA

Travel

• Attendance and participation in national and international conferences encouraged

Compensation and Benefits:
The expected base salary range for this position is $90,000 - $140,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s level qualifications, experience, and skills.
While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.
SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.
SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.