Senior Scientist II, Hepatocyte Engineering & Liver Tissue

Harvard University FAS Human Resources; Boston (MA); On-site; USD 130,000 - 180,000; Full time

Benefits offered by this job

Medical, dental & vision insurance

Tuition assistance & professional dev.

Generous paid time off

Job summary

Wyss Institute at Harvard University seeks a Senior Scientist II to provide scientific and technical leadership for hepatocyte engineering within a multi-institutional program developing engineered liver tissue. You will expand, engineer and characterize functional human hepatocytes, including immune-modulatory strategies, and integrate cells into tissue constructs and in vivo studies.

You will design core experiments, collaborate across teams, mentor staff, and contribute to translational

Qualifications

• Master’s degree in Cell Biology, Molecular Biology, Bioengineering or related field with 9+ years of relevant research experience.
• Experience with human cell culture, expansion and functional characterization.
• Strong background in molecular biology and genome engineering including CRISPR/Cas9 and gene delivery.

Responsibilities

• Lead hepatocyte workstream experiments, planning and analysis; solve novel technical challenges.
• Collaborate with biofabrication, vascularization and in vivo teams to integrate hepatocytes into tissue constructs.
• Lead milestone planning, sponsor reporting and program reviews; contribute to publications and grant activities.
• Mentor researchers and staff; ensure rigorous documentation and safe lab operations.

Skills

Hepatocyte culture

CRISPR/Cas9 editing

Genome engineering

3D culture/organoids

Education

Master’s degree in Cell Biology or related field

Tools

CRISPR/Cas9

Gene delivery (viral/non-viral)

Job description

Wyss Institute at Harvard University seeks a Senior Scientist II to provide scientific and technical leadership for hepatocyte engineering within a multi-institutional program developing engineered liver tissue. You will expand, engineer and characterize functional human hepatocytes, including immune-modulatory strategies, and integrate cells into tissue constructs and in vivo studies.

You will design core experiments, collaborate across teams, mentor staff, and contribute to translational