Senior Scientist / Engineer (Human Physiology Systems / Bioengineering)

ecsfederal; Virginia (MN); Hybrid; USD 145,000 - 240,000; Full time

Job summary

ecsfederal is seeking a Senior Scientist/Engineer serving as a Scientific Engineering Technical Advisor (SETA) to support an ARPA-H Program Manager. The role emphasizes tissue and organoid manufacturing, organ preservation, and ex vivo perfusion within a translational bioengineering context.

This remote position requires a strong technical-to-clinical translation mindset and the ability to work across disciplines.

Qualifications

• Advanced degree in a relevant field is required.
• Experience synthesizing complex scientific information into concise written and visual products for decision support.
• Subject-matter expertise in organ preservation, ex vivo perfusion, and transplant biology is preferred.
• Ability to evaluate technical data, experimental plans, and development pathways.
• Must be able to obtain a federal government Public Trust clearance.

Responsibilities

• Provide technical and strategic support across ARPA-H program portfolio.
• Evaluate technologies in the context of clinical workflows and transplantation logistics.
• Conduct landscape analyses and technical diligence on emerging capabilities.
• Draft recommendations and briefing materials for program decision-makers.
• Identify subject-matter experts and potential performers across academia, industry, and government.
• Assist in program management tasks including meetings and site visits.

Skills

tissue organoid manufacturing

regenerative medicine

transplantation

bioengineering

multidisciplinary collaboration

Education

PhD in physiology or related

MD with transplantation experience

Job description

ECS is seeking aSenior Scientist/Engineer with a mix of expertise in human physiology systems, regenerative medicine, and transplantation to serve as a Scientific Engineering Technical Advisor (SETA) to support an ARPA-H Program Manager and work in ourRemote office.

In this role, you will collaborate with the ARPA-H Program Manager and team to effectuate bold ARPA-H research initiatives, support the development, funding, and management of new and existing R&D programs to meet ARPA-H’s mission to accelerate better health outcomes for everyone. This role will support the management of programs and projects in topics pertaining to human physiology systems and bioengineering.

The ideal candidate will have appropriate technical training in human physiology systems and will bring deep technical expertise in regenerative medicine and/or transplantation, along with the ability to assess emerging technologies in the context of clinical workflow, manufacturability, regulatory constraints, and real-world implementation. This role is best suited for an individual who is scientifically rigorous, comfortable operating across disciplines, and able to translate between basic science, engineering development, and clinical/transplant operational realities.

The successful candidate will help ARPA-H engage high-potential technical approaches at the intersection of bioengineering, transplantation, and advanced therapeutic manufacturing. This role requires someone who can bridge science, engineering, and implementation realities to support ambitious, high-impact programs. This is a remote position.

These SETA duties include but are not limited to:

• Provide technical and strategic support across a portfolio of programs related to tissue and organoid manufacturing, tissue and organ preservation, ex vivo organ perfusion and diagnostics, and other translational technologies relevant to tissue and organ recovery, preservation, and transplantation.
• Evaluate technologies in the context of clinical and operational realities, including donor tissue and organ recovery, preservation logistics, perfusion-enabled assessment/intervention, and transplant-center workflow.
• Conduct landscape analyses and technical diligence on emerging capabilities, vendors, performers, and scientific trends and advise on the scientific plausibility, translational feasibility, manufacturability, and adoption potential of proposed approaches.
• Provide insight into how innovations may intersect with the broader transplant ecosystem, including organ procurement organizations, transplant centers, and applicable federal regulators and stakeholders.
• Maintain awareness of relevant scientific, clinical, regulatory, and market developments.
• Review and assess technical proposals, performer submissions, milestones, deliverables, and program risks. Provide feedback, organize reviewer comments, draft recommendations and project summaries, and presentation materials.
• Help identify subject-matter experts, potential performers, test/evaluation partners, and transition stakeholders across academia, industry, clinical practice, and government.
• Assist in program management functions, including preparing for technical meetings, conducting site visits, consolidating performer progress, identifying schedule risks, and creating briefing materials.
• Some CONUS travel is expected (~10-20%) as needed to fully support the Program Manager and Program.

Salary Range: $145,000 - $240,000

General Description of Benefits

• Advanced degree in a relevant field, such as:
• PhD in physiology, systems biology, bioengineering, tissue engineering, regenerative medicine, or related discipline;or
• MD with significant experience in transplantation, organ preservation, transplant surgery, transplant medicine, or a closely related field.
• Experience synthesizing complex scientific information into concise written and visual products for decision support.
• Demonstrated subject-matter expertise in one or more of the following: organ preservation, ex vivo organ perfusion and diagnostics, transplant biology, regenerative medicine, translational bioengineering
• Ability to critically evaluate technical data, experimental plans, and development pathways.
• Team-oriented with strong interpersonal skills and the ability to work across multidisciplinary teams
• Experience supporting complex R&D efforts involving academic, clinical, and/or industrial stakeholders.
• Must be able to obtain a federal government Public Trust clearance.