Senior Scientist, Digital Pathology & AI Informatics

BioSpace; Philadelphia (Philadelphia County); Hybrid; USD 150,000 - 190,000; Full time

Benefits offered by this job

Competitive benefits package

Discretionary annual bonus

Stock-based incentives

Flexible work models

Job summary

Amgen is seeking a Senior Scientist to join the Computational Imaging and Digital Biomarkers team. You will develop computational approaches for digital pathology and spatial biology data, extracting biologically interpretable insights from tissue and integrating morphology, cell phenotypes, and molecular measurements to understand tumor microenvironment and biomarker discovery.

The role emphasizes applying H&E foundation models, working with pathologists and computational biologists, and

Qualifications

• Doctorate degree required or equivalent experience in computational biology, bioinformatics, biomedical engineering, computer science, or related field.
• Strong background in spatial biology, digital pathology, or related imaging analyses.
• Experience with Python, R, and ML methods for large biomedical datasets.

Responsibilities

• Design and apply spatial analysis approaches to tissue organization and cellular interactions.
• Develop and apply computational pathology workflows for digitized whole slide images.
• Evaluate and adapt H&E foundation models for pathology image analysis.
• Collaborate with pathologists and translational scientists to translate questions into robust analyses.
• Build reproducible Python and R-based workflows for preprocessing, analysis, and reporting.
• Present methods and findings to technical and non-technical audiences.

Skills

Spatial analysis

Python

R

Machine learning

Communication

Team collaboration

Data visualization

Spatial transcriptomics

Education

Doctorate degree

Masters degree with relevant experience

Bachelors degree with relevant experience

Tools

Python

R

OpenCV

AWS

Cloud computing

H&E foundation models

Job description

Amgen is seeking a Senior Scientist to join the Computational Imaging and Digital Biomarkers team. You will develop computational approaches for digital pathology and spatial biology data, extracting biologically interpretable insights from tissue and integrating morphology, cell phenotypes, and molecular measurements to understand tumor microenvironment and biomarker discovery.

The role emphasizes applying H&E foundation models, working with pathologists and computational biologists, and