Senior Scientist, CAR-T Safety & Preclinical Innovation

Bristol-Myers Squibb Co; Seattle (WA); On-site; USD 137,000 - 166,000; Full time

Benefits offered by this job

Flexible Time Off

11 holidays

Competitive benefits

Job summary

Bristol Myers Squibb seeks a research scientist to advance Cell Therapy safety, focusing on ex vivo and in vivo CAR-T approaches in Seattle. The role emphasizes preclinical safety evaluation, development of in vitro models, and collaboration with teams to translate findings into safer therapies.

Applicants should have extensive experience in flow cytometry, molecular assays, and cell culture, with a strong publication record and clear communication skills for presenting results to stakeholders.

Qualifications

• Bachelor's degree with 7+ years, Master's with 5+ years, or PhD with 2+ years of relevant academic/industry experience.
• Strong publication record and/or scientific presentations.
• Experience designing, executing, and interpreting in vitro functional assays for immunology, gene editing, or cell therapy.

Responsibilities

• Collaborate to evaluate ex vivo CAR and in vivo CAR T-cell products and tackle toxicology challenges.
• Design and execute experiments to predict on- and off-target risks using cell/tissue-based models.
• Build expertise in engineered T-cell therapies focusing on preclinical safety evaluation and data reporting.
• Communicate findings to project teams with presentations and technical reports.
• Deliver on short-term goals while driving innovation in safety evaluation for T-cell therapies.

Skills

Ex vivo CAR T-cell design

In vivo CAR T-cell safety

Flow cytometry

Molecular assays

Cell culture primary cells

Gene editing

ddPCR

ELISA

Luminex

MSD assays

Incucyte live-cell imaging

Western blotting

FlowJo software

Education

Bachelor's degree + 7+ years

Master's degree + 5+ years

PhD + 2+ years

Tools

FlowJo

Incucyte

Luminex

MSD

ddPCR

ELISA

Western blotting

Job description

Bristol Myers Squibb seeks a research scientist to advance Cell Therapy safety, focusing on ex vivo and in vivo CAR-T approaches in Seattle. The role emphasizes preclinical safety evaluation, development of in vitro models, and collaboration with teams to translate findings into safer therapies.

Applicants should have extensive experience in flow cytometry, molecular assays, and cell culture, with a strong publication record and clear communication skills for presenting results to stakeholders.