Senior Scientist, Biologics Engineering — Protein & Antibody

Biogen; Cambridge (MA); On-site; USD 124,000 - 166,000; Full time

Benefits offered by this job

Medical, Dental, Vision, & Life ins.

Tuition reimbursement

401(k) program with match

Paid vacation and holidays

Employee stock purchase plan

Job summary

Biogen is seeking an experienced Sr. Scientist in the BioDesign group to contribute to discovery and development of biologic therapeutics.

The role combines hands-on molecular biology, protein engineering, and mammalian cell engineering with oversight of CRO production efforts. You will design and express recombinant proteins and antibodies, build stable cell lines, and lead characterization and purification activities, while collaborating across multidisciplinary teams to advance therapeutic

Qualifications

• Ph.D. with 2+ years industry experience or M.S. with 6+ years industry experience.
• Strong expertise in molecular biology and protein engineering, including antibody design.
• Hands-on mammalian cell culture, transfection, and expression workflows.

Responsibilities

• Design, engineer, and express recombinant proteins and antibodies, including bispecifics and fusions.
• Develop stable CHO and mammalian cell lines for expression and screening.
• Support protein purification and characterization, incl. flow-based target engagement.
• Manage protein production activities at CROs and oversee external work.
• Present findings at team meetings and document work in ELNs.

Skills

Molecular biology

Protein engineering

Mammalian cell culture

Flow cytometry (FACS)

Project coordination

Data presentation

Documentation

Education

Ph.D. in biochemistry or related field

M.S. with 6+ years industry experience

Tools

SEC

Octet

FACS instrumentation

Job description

Biogen is seeking an experienced Sr. Scientist in the BioDesign group to contribute to discovery and development of biologic therapeutics.

The role combines hands-on molecular biology, protein engineering, and mammalian cell engineering with oversight of CRO production efforts. You will design and express recombinant proteins and antibodies, build stable cell lines, and lead characterization and purification activities, while collaborating across multidisciplinary teams to advance therapeutic